Monique A.J. van der Vleuten

The Preclinical Profile of the Duocarmycin-Based HER2-Targeting ADC SYD985 Predicts for Clinical Benefit in Low HER2-Expressing Breast Cancers

Miranda M.C. van der Lee, Patrick G. Groothuis, Ruud Ubink et al. · Molecular Cancer Therapeutics · 2015 · 215 citations

Pharmacy, Oncology, Pharmacology +16

CYP7B expression and activity in fibroblast‐like synoviocytes from patients with rheumatoid arthritis: Regulation by proinflammatory cytokines

John Dulos, Monique A.J. van der Vleuten, Annemieke Kavelaars et al. · Arthritis & Rheumatism · 2005 · 58 citations · Full text

Medicine, Molecular Biology, Pharmacology +14

Unraveling the Interaction between Carboxylesterase 1c and the Antibody–Drug Conjugate SYD985: Improved Translational PK/PD by Using Ces1c Knockout Mice

Ruud Ubink, Eef H.C. Dirksen, Myrthe Rouwette et al. · Molecular Cancer Therapeutics · 2018 · 50 citations · Full text

Pharmacy, Pharmacokinetics, Pharmacology +17

Preclinical Profile of BYON3521 Predicts an Effective and Safe MET Antibody–Drug Conjugate

Patrick G. Groothuis, Daniëlle C.H. Jacobs, Inge A.T. Hermens et al. · Molecular Cancer Therapeutics · 2023 · 11 citations · Full text

Pharmacy, Oncology, Pharmacology +17