Gabrielle St‐Pierre

Development of a Commercial Manufacturing Process for Sotorasib, a First-in-Class KRAS^G12C Inhibitor

Liang Zhang, Daniel J. Griffin, Matthew G. Beaver et al. · Organic Process Research & Development · 2022 · 29 citations

Combinatorial Chemistry, Medicinal Chemistry, Pharmaceutical Chemistry +12

A New Approach to Explore the Binding Space of Polysaccharide-Based Ligands: Selectin Antagonists

Mickael Calosso, Daniel Charpentier, Marc Vaillancourt et al. · ACS Medicinal Chemistry Letters · 2012 · 19 citations · Full text

Polysaccharide Ligand, Glycobiology, Polysaccharide +18

Axial Chirality in the Sotorasib Drug Substance, Part 1: Development of a Classical Resolution to Prepare an Atropisomerically Pure Sotorasib Intermediate

Andrew T. Parsons, Seb Caille, Marc A. Caporini et al. · Organic Process Research & Development · 2022 · 19 citations

Combinatorial Chemistry, Bioorganic Chemistry, Sotorasib Drug Substance +20

Accelerated Development of a Scalable Ring-Closing Metathesis to Manufacture AMG 176 Using a Combined High-Throughput Experimentation and Computational Modeling Approach

Gabrielle St‐Pierre, Alan H. Cherney, Wencan Chen et al. · Organic Process Research & Development · 2020 · 17 citations

Materials Science, Medicinal Chemistry, Accelerated Development +15

Solution and Solid-Phase Stereocontrolled Synthesis of 1,2-<i>cis</i>-Glycopyranosides with Minimally Protected Glycopyranosyl Donors Catalyzed by BF₃–<i>N</i>,<i>N</i>-Dimethylformamide Complex

Gabrielle St‐Pierre, Stephen Hanessian · Organic Letters · 2016 · 13 citations

Enantioselective Synthesis, Glycosylation, Alcohol Acceptors +15