Troels Koch

Silencing of microRNA families by seed-targeting tiny LNAs

Susanna Obad, Camila O. dos Santos, Andreas Petri et al. · Nature Genetics · 2011 · 624 citations

Microrna Families, Genetics, Microrna Detection +5

Efficient gene silencing by delivery of locked nucleic acid antisense oligonucleotides, unassisted by transfection reagents

C.A. Stein, Jens Bo Hansen, Johnathan C. Lai et al. · Nucleic Acids Research · 2009 · 376 citations · Full text

Engineering, Molecular Biology, Gene Delivery +20

Solid‐Phase synthesis of peptide nucleic acids

Leif Christensen, Richard Fitzpatrick, Brian Gildea et al. · Journal of Peptide Science · 1995 · 334 citations

Short locked nucleic acid antisense oligonucleotides potently reduce apolipoprotein B mRNA and serum cholesterol in mice and non-human primates

Ellen Marie Straarup, Niels Fisker, Maj Hedtjärn et al. · Nucleic Acids Research · 2010 · 244 citations · Full text

PCSK9 LNA Antisense Oligonucleotides Induce Sustained Reduction of LDL Cholesterol in Nonhuman Primates

Marie Lindholm, Joacim Elmén, Niels Fisker et al. · Molecular Therapy · 2011 · 145 citations · Full text