Serena J. Silver

Systematic RNA interference reveals that oncogenic KRAS-driven cancers require TBK1

David A. Barbie, Pablo Tamayo, Jesse S. Boehm et al. · Nature · 2009 · 4.1K citations · Full text

Systems Biology, Oncogenic Agent, Medicine +4

A Next Generation Connectivity Map: L1000 Platform and the First 1,000,000 Profiles

Aravind Subramanian, Rajiv Narayan, Steven M. Corsello et al. · Cell · 2017 · 3.5K citations · Full text

Network Science, Engineering, Data Science +12

The JAK2/STAT3 signaling pathway is required for growth of CD44+CD24– stem cell–like breast cancer cells in human tumors

Lauren L Campbell Marotta, Vanessa Almendro, Andriy Marusyk et al. · Journal of Clinical Investigation · 2011 · 918 citations

Breast Oncology, Immunology, Cell Proliferation +21

Subtype-specific genomic alterations define new targets for soft-tissue sarcoma therapy

Jordi Barretina, Barry S. Taylor, Shantanu Banerji et al. · Nature Genetics · 2010 · 711 citations · Full text

Tumor Heterogeneity, Medicine, Pathology +6

Project DRIVE: A Compendium of Cancer Dependencies and Synthetic Lethal Relationships Uncovered by Large-Scale, Deep RNAi Screening

E. Robert McDonald, Antoine de Weck, Michael R. Schlabach et al. · Cell · 2017 · 687 citations · Full text

Bioinformatics, Tumor Biology, Radiation Oncology +13