Anton Leighton

Lenercept (p55 tumor necrosis factor receptor fusion protein) in severe sepsis and early septic shock: A randomized, double-blind, placebo-controlled, multicenter phase III trial with 1,342 patients

Edward Abraham, Pierre-François Laterre, Jorge Garbino et al. · Critical Care Medicine · 2001 · 291 citations

Assessment of the safety of recombinant tissue factor pathway inhibitor in patients with severe sepsis: A multicenter, randomized, placebo-controlled, single-blind, dose escalation study

Edward Abraham, Konrad Reinhart, Petr Svoboda et al. · Critical Care Medicine · 2001 · 252 citations

Tolerability, Pharmacokinetics, and Serum Bactericidal Activity of Intravenous Dalbavancin in Healthy Volunteers

Anton Leighton, Alice B. Gottlieb, Daniela Jabés et al. · Antimicrobial Agents and Chemotherapy · 2004 · 187 citations · Full text

Female Volunteers, Antibiotic Adjuvant, Pharmacotherapy +18

A High-Affinity Native Human Antibody Disrupts Biofilm from Staphylococcus aureus Bacteria and Potentiates Antibiotic Efficacy in a Mouse Implant Infection Model

Angeles Estellés, Anne-Kathrin Woischnig, Keyi Liu et al. · Antimicrobial Agents and Chemotherapy · 2016 · 81 citations · Full text

Trl1068in Vivowas, Pathogenic Microbiology, Microbial Pathogens +22

A Human Biofilm-Disrupting Monoclonal Antibody Potentiates Antibiotic Efficacy in Rodent Models of both Staphylococcus aureus and Acinetobacter baumannii Infections

Yan Q. Xiong, Angeles Estellés, Liang Li et al. · Antimicrobial Agents and Chemotherapy · 2017 · 57 citations · Full text