Andrew M. Spence

UNC-5, a transmembrane protein with immunoglobulin and thrombospondin type 1 domains, guides cell and pioneer axon migrations in C. elegans

Chungyee Leung-Hagesteijn, Andrew M. Spence, Brian D. Stern et al. · Cell · 1992 · 405 citations

Developmental Biology, Signal Transduction, Medicine +11

Direct protein–protein interaction between the intracellular domain of TRA-2 and the transcription factor TRA-1A modulates feminizing activity in <i>C. elegans</i>

David H. Lum, Patricia E. Kuwabara, David Zarkower et al. · Genes & Development · 2000 · 397 citations · Full text

Xx Germ Line, Molecular Regulation, Genetics +16

The distal transcription signals of the herpesvirus tk gene share a common hexanucleotide control sequence

Steven L. McKnight, Robert C. Kingsbury, Andrew M. Spence et al. · Cell · 1984 · 272 citations · Full text

Viral Replication, Molecular Virology, Natural Sciences +11

The product of fem-1, a nematode sex-determining gene, contains a motif found in cell cycle control proteins and receptors for cell-cell interactions

Andrew M. Spence · Cell · 1990 · 176 citations

Cell-cell Interactions, Cell Division, Germ Cell +8

A CUL-2 Ubiquitin Ligase Containing Three FEM Proteins Degrades TRA-1 to Regulate C. elegans Sex Determination

Natalia G. Starostina, Jae‐Min Lim, Mara Schvarzstein et al. · Developmental Cell · 2007 · 139 citations · Full text

Transcriptional Regulation, Developmental Biology, Sex Determination +12