Daniele Pietra

Synthesis and Biological Evaluation of 2,3,5-Substituted [1,2,4]Thiadiazoles as Allosteric Modulators of Adenosine Receptors

Adrianus M. C. H. van den Nieuwendijk, Daniele Pietra, Laura H. Heitman et al. · Journal of Medicinal Chemistry · 2004 · 81 citations · Full text

Allosteric Modulators, Adenosine Receptors, Pharmacotherapy +16

Design and synthesis of 2-oxindole based multi-targeted inhibitors of PDK1/Akt signaling pathway for the treatment of glioblastoma multiforme

Simona Sestito, Giulia Nesi, Simona Daniele et al. · European Journal of Medicinal Chemistry · 2015 · 47 citations · Full text

Neuro-oncology, Medicinal Chemistry, Glioma +10

Synthesis and biological evaluation of 2-aminothiazoles and their amide derivatives on human adenosine receptors. Lack of effect of 2-aminothiazoles as allosteric enhancers

Anikó Göblyös, Sabrina Neves Santiago, Daniele Pietra et al. · Bioorganic & Medicinal Chemistry · 2005 · 36 citations

Molecular Pharmacology, Allosteric Enhancers, Biochemistry +9

Synthesis, biological activity and molecular modelling of new trisubstituted 8-azaadenines with high affinity for A1 adenosine receptors

Irene Giorgi, Anna Maria Bianucci, Giuliana Biagi et al. · European Journal of Medicinal Chemistry · 2006 · 27 citations · Full text

Biological Activity, Combinatorial Chemistry, Biochemistry +8

N6-1,3-Diphenylurea derivatives of 2-phenyl-9-benzyladenines and 8-azaadenines: Synthesis and biological evaluation as allosteric modulators of A2A adenosine receptors

Irene Giorgi, Giuliana Biagi, Anna Maria Bianucci et al. · European Journal of Medicinal Chemistry · 2007 · 26 citations · Full text

Allosteric Modulators, A2a Adenosine Receptors, Biochemistry +7