Leslie J. Browne

Development of a large-scale chemogenomics database to improve drug candidate selection and to understand mechanisms of chemical toxicity and action

Brigitte Ganter, Stuart Tugendreich, Cecelia I. Pearson et al. · Journal of Biotechnology · 2005 · 286 citations

Drug Target, Engineering, Predictive Toxicology +15

Asymmetric total synthesis of erythromcin. 1. Synthesis of an erythronolide A secoacid derivative via asymmetric induction

R. B. Woodward, Eugene W. Logusch, K. P. Nambiar et al. · Journal of the American Chemical Society · 1981 · 257 citations

Derivative (Chemistry), Biosynthesis, Derivatives +14

Fadrozole hydrochloride: a potent, selective, nonsteroidal inhibitor of aromatase for the treatment of estrogen-dependent disease

Leslie J. Browne, Candido Gude, Ronald E. Steele et al. · Journal of Medicinal Chemistry · 1991 · 222 citations · Full text

Hormonal Contraceptive, Cgs 16949, Pharmacotherapy +20

In vitro and in vivo studies demonstrating potent and selective estrogen inhibition with the nonsteroidal aromatase inhibitor CGS 16949A

Ronald E. Steele, Lynn B. Mellor, Wilbur K. Sawyer et al. · Steroids · 1987 · 216 citations

Molecular Pharmacology, Hormonal Contraceptive, Vivo Studies +9

Asymmetric total synthesis of erythromycin. 3. Total synthesis of erythromycin

R. B. Woodward, Eugene W. Logusch, K. P. Nambiar et al. · Journal of the American Chemical Society · 1981 · 201 citations

Pharmaceutical Science, Biochemistry, Natural Sciences +12