Kyoko Manabe

Oxidative metabolism of omeprazole in human liver microsomes: cosegregation with S-mephenytoin 4'-hydroxylation.

Kazuhiro Chiba, Kazuo Kobayashi, Kyoko Manabe et al. · Journal of Pharmacology and Experimental Therapeutics · 1993 · 145 citations

Medicine, Biochemistry, Pharmacology +17

Comparison of the kinetic disposition and metabolism of E3810, a new proton pump inhibitor, and omeprazole in relation to S-mephenytoin 4′-hydroxylation status

Sanae Yasuda, Yukio Horai, Yoshiro Tomono et al. · Clinical Pharmacology & Therapeutics · 1995 · 138 citations

Pharmacy, Pharmacokinetics, Pharmacology +14

Comparison of the interaction potential of a new proton pump inhibitor, E3810, versus omeprazole with diazepam in extensive and poor metabolizers of S-mephenytoin 4′-hydroxylation*

Takashi Ishizaki, Kan Chiba, Kyoko Manabe et al. · Clinical Pharmacology & Therapeutics · 1995 · 79 citations

Medicine, Pharmacology, Pharmacotherapy +16

Development and preliminary application of a simple assay of S-mephenytoin 4-hydroxylase activity in human liver microsomes

Kazuhiro Chiba, Kyoko Manabe, Kaoru Kobayashi et al. · European Journal of Clinical Pharmacology · 1993 · 44 citations

Medicine, Biochemistry, Pharmacology +15

The kinetic characterization of S-mephenytoin 4-hydroxylase (P-450IICMP) activity in human liver samples obtained as surgical waste from Japanese patients.

Kazuhiro Chiba, Kazuo Kobayashi, M Tani et al. · Drug Metabolism and Disposition · 1993 · 11 citations

Medicine, Biochemistry, Pharmacology +17