Keelan Z. Guiley - Concepedia

Concepedia

Author

Keelan Z. Guiley

Howard Hughes Medical Institute ORCID

Also Known As

K.Z. Guiley, Keelan G. Guiley, Keelan Guiley, Keelan Z Guiley, Keelan Z. Guiley

63

Publications

1.2K

Citations

12

H-Index

20

Concepts

All Affiliations

Howard Hughes Medical Institute University of California, Santa Cruz University of California, San Francisco University of California, Berkeley Virginia Commonwealth University

KZ

About

Keelan Z. Guiley is an author at Howard Hughes Medical Institute specializing in medicine, cell signaling, and cell biology.

Top Concepts

#	Concept	H-Index	Publications	Citations
1	Medicine	2	2	296
2	Cell Biology	2	2	296
3	Natural Sciences	1	1	217
4	Molecular Biology	1	1	217
5	Pharmacology	1	1	226

Keelan Z. Guiley

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14

Publications

1.2K

Citations

12

H-Index

	Year	Citations
p27 allosterically activates cyclin-dependent kinase 4 and antagonizes palbociclib inhibition Keelan Z. Guiley, Jack W. Stevenson, Kevin Lou, Science PharmacotherapyTumor BiologyMolecular PharmacologySignaling PathwayCell Regulation	2019	226
The molecular architecture of human Dicer Pick‐Wei Lau, Keelan Z. Guiley, Nabanita De, Nature Structural & Molecular Biology Natural SciencesMacromolecular MachineDna ReplicationMolecular BiologyStructural Biology	2012	217
Chemoselective Covalent Modification of K-Ras(G12R) with a Small Molecule Electrophile Ziyang Zhang, Johannes Morstein, Andrew K. Ecker, Journal of the American Chemical Society	2022	142
Chemical acylation of an acquired serine suppresses oncogenic signaling of K-Ras(G12S) Ziyang Zhang, Keelan Z. Guiley, Kevan M. Shokat Nature Chemical Biology	2022	136
Structural mechanisms of DREAM complex assembly and regulation Keelan Z. Guiley, Tyler Liban, Jessica Felthousen, Genes & Development	2015	117
A Small Molecule Reacts with the p53 Somatic Mutant Y220C to Rescue Wild-type Thermal Stability Keelan Z. Guiley, Kevan M. Shokat Cancer Discovery	2022	84
The cell cycle regulatory DREAM complex is disrupted by high expression of oncogenic B-Myb Audra N. Iness, Jessica Felthousen, Varsha Ananthapadmanabhan, Oncogene Cell RegulationCell DivisionOncogenic B-mybGene ExpressionHigh Expression	2018	70
Strain-release alkylation of Asp12 enables mutant selective targeting of K-Ras-G12D Qinheng Zheng, Ziyang Zhang, Keelan Z. Guiley, Nature Chemical Biology	2024	64
Structural mechanism of Myb–MuvB assembly Keelan Z. Guiley, Audra N. Iness, Siddharth Saini, Proceedings of the National Academy of Sciences	2018	38
Targeting Ras-, Rho-, and Rab-family GTPases via a conserved cryptic pocket Johannes Morstein, Micah C. Fernando, Yue Yang, Cell	2024	37

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