Antonin de Fougerolles

Rational design of cationic lipids for siRNA delivery

Sean C. Semple, Akin Akinc, Jianxin Chen et al. · Nature Biotechnology · 2010 · 1.7K citations

Lipid Preparation, Nanomedicine, Engineering +3

Sequence-specific potent induction of IFN-α by short interfering RNA in plasmacytoid dendritic cells through TLR7

Veit Hornung, Margit Guenthner‐Biller, Carole Bourquin et al. · Nature Medicine · 2005 · 1.2K citations · Full text

Innate Immune System, Immunology, Immune Regulation +16

A combinatorial library of lipid-like materials for delivery of RNAi therapeutics

Akin Akinc, Andreas Zumbuehl, Michael S. Goldberg et al. · Nature Biotechnology · 2008 · 1.2K citations

Cell-based Drug Delivery, Nanomedicine, Lipid Preparation +9

Targeted Delivery of RNAi Therapeutics With Endogenous and Exogenous Ligand-Based Mechanisms

Akin Akinc, William Querbes, Soma De et al. · Molecular Therapy · 2010 · 1.1K citations · Full text

Nanotherapeutics, Engineering, Immunology +17

Lipid-like materials for low-dose, in vivo gene silencing

Kevin T. Love, Kerry P. Mahon, Christopher G. Levins et al. · Proceedings of the National Academy of Sciences · 2010 · 952 citations · Full text

In Vivo Gene Therapy, Immunology, Gene Delivery +18