Tolbutamide Controls Glucagon Release From Mouse Islets Differently Than Glucose

Rui Cheng, Ana Gómez-Ruiz, Nancy Antoine, +6

Diabetes

Experimental PharmacologyCellular PhysiologyInsulin SignalingGastrointestinal Peptide HormoneMetabolic Syndrome +17

SGLT2 is not expressed in pancreatic α- and β-cells, and its inhibition does not directly affect glucagon and insulin secretion in rodents and humans

Heeyoung Chae, Robert Augustin, Eva Gatineau, +20

Molecular Metabolism

NNT reverse mode of operation mediates glucose control of mitochondrial NADPH and glutathione redox state in mouse pancreatic β-cells

Laila R.B. Santos, Carole Muller, Arnaldo Henrique de Souza, +6

Molecular Metabolism

Somatostatin Is Only Partly Required for the Glucagonostatic Effect of Glucose but Is Necessary for the Glucagonostatic Effect of KATP Channel Blockers

Bao-Khanh Lai, Heeyoung Chae, Ana Gómez-Ruiz, +8

Diabetes

Katp Channel BlockersKatp Channel AblationCellular PhysiologyInsulin SignalingGastrointestinal Peptide Hormone +17

A Triple-Mode Flexible E-Skin Sensor Interface for Multi-Purpose Wearable Applications

Sung‐Woo Kim, Youngoh Lee, Jonghwa Park, +4

Sensors

Wearable SystemEngineeringElectronic SkinWearable TechnologyWearable Sensors +14

In depth functional characterization of human induced pluripotent stem cell-derived beta cells in vitro and in vivo

Federica Fantuzzi, Sanna Toivonen, Andréa Alex Schiavo, +15

Frontiers in Cell and Developmental Biology

GLP-1R agonists demonstrate potential to treat Wolfram syndrome in human preclinical models

Vyron Gorgogietas, Bahareh Rajaei, Heeyoung Chae, +21

Diabetologia

Metallothionein 1 negatively regulates glucose-stimulated insulin secretion and is differentially expressed in conditions of beta cell compensation and failure in mice and humans

Mohammed Bensellam, Yan‐Chuan Shi, Jeng Yie Chan, +7

Diabetologia

Metabolic SyndromeBeta Cell CompensationInsulin SignalingHealth SciencesMedicine +11

The lack of functional nicotinamide nucleotide transhydrogenase only moderately contributes to the impairment of glucose tolerance and glucose-stimulated insulin secretion in C57BL/6J vs C57BL/6N mice

Anne-Françoise Close, Heeyoung Chae, Jean‐Christophe Jonas

Diabetologia

Metabolic SyndromeGlucose ToleranceEnergy MetabolismBiochemistryMedicine +10

KATP channel blockers control glucagon secretion by distinct mechanisms: A direct stimulation of α-cells involving a [Ca2+]c rise and an indirect inhibition mediated by somatostatin

Bilal Singh, Firas Khattab, Heeyoung Chae, +3

Molecular Metabolism