Mitophagy Directs Muscle-Adipose Crosstalk to Alleviate Dietary Obesity

Tingting Fu, Zhisheng Xu, Lin Liu, +10

Cell Reports

FAM64A positively regulates STAT3 activity to promote Th17 differentiation and colitis-associated carcinogenesis

Zhisheng Xu, Hongxia Zhang, Weiwei Li, +9

Proceedings of the National Academy of Sciences

Disuse-associated loss of the protease LONP1 in muscle impairs mitochondrial function and causes reduced skeletal muscle mass and strength

Zhisheng Xu, Tingting Fu, Qiqi Guo, +17

Nature Communications

Histone methyltransferase MLL4 controls myofiber identity and muscle performance through MEF2 interaction

Lin Liu, Chenyun Ding, Tingting Fu, +17

Journal of Clinical Investigation

Histone ModificationsMuscle FunctionEpigenetic ChangeMolecular BiologyMetabolic Remodeling +20

Coupling of COPII vesicle trafficking to nutrient availability by the IRE1α-XBP1s axis

Lin Liu, Jie Cai, Huimin Wang, +19

Proceedings of the National Academy of Sciences

Protein SecretionMolecular RegulationMolecular BiologyNutrient AvailabilityCellular Physiology +22

Mitochondrial proteostasis stress in muscle drives a long-range protective response to alleviate dietary obesity independently of ATF4

Qiqi Guo, Zhisheng Xu, Danxia Zhou, +18

Science Advances

LDLR is an entry receptor for Crimean-Congo hemorrhagic fever virus

Zhisheng Xu, Wen-Tian Du, Suyun Wang, +7

Cell Research

AMPK-dependent and -independent coordination of mitochondrial function and muscle fiber type by FNIP1

Liwei Xiao, Jing Liu, Zongchao Sun, +19

PLoS Genetics

-Independent CoordinationSkeletal Muscle CellsMitophagyMuscle FunctionCytoskeleton +14

Proteolytic rewiring of mitochondria by LONP1 directs cell identity switching of adipocytes

Tingting Fu, Wanping Sun, Jiachen Xue, +21

Nature Cell Biology

Lonp1 DirectsSignal TransductionMitochondrial FunctionProteolytic RewiringCell Signaling +10

FNIP1 regulates adipocyte browning and systemic glucose homeostasis in mice by shaping intracellular calcium dynamics

Yujing Yin, Dengqiu Xu, Yan Mao, +15

The Journal of Experimental Medicine