Flavian D. Brown

Subsets of exhausted CD8+ T cells differentially mediate tumor control and respond to checkpoint blockade

Brian C. Miller, Debattama R. Sen, Rose Al Abosy et al. · Nature Immunology · 2019 · 1.9K citations · Full text

Mediate Tumor Control, Cancer Immunosurveillance, Immunology +8

In vivo CRISPR screening identifies Ptpn2 as a cancer immunotherapy target

Robert T. Manguso, Hans W. Pope, Margaret D. Zimmer et al. · Nature · 2017 · 1.1K citations · Full text

Identifies Ptpn2, Vivo Crispr, Immunology +8

The epigenetic landscape of T cell exhaustion

Debattama R. Sen, James J. Kaminski, R. Anthony Barnitz et al. · Science · 2016 · 909 citations · Full text

Loss of ADAR1 in tumours overcomes resistance to immune checkpoint blockade

Jeffrey J. Ishizuka, Robert T. Manguso, Collins Cheruiyot et al. · Nature · 2018 · 688 citations · Full text

Cancer Immunosurveillance, Tumours Overcomes Resistance, Medicine +8

Stable inhibitory activity of regulatory T cells requires the transcription factor Helios

Hye‐Jung Kim, R. Anthony Barnitz, Taras Kreslavsky et al. · Science · 2015 · 411 citations