Tatsuya Takemoto

Functional Analysis of Chicken Sox2 Enhancers Highlights an Array of Diverse Regulatory Elements that Are Conserved in Mammals

Masanori Uchikawa, Yoshiko Ishida, Tatsuya Takemoto et al. · Developmental Cell · 2003 · 404 citations · Full text

Knockout Mouse, Transcriptional Regulation, Developmental Biology +9

Restriction of PD-1 function by <i>cis</i> -PD-L1/CD80 interactions is required for optimal T cell responses

Daisuke Sugiura, Takumi Maruhashi, Il‐mi Okazaki et al. · Science · 2019 · 357 citations

Electroporation enables the efficient mRNA delivery into the mouse zygotes and facilitates CRISPR/Cas9-based genome editing

Masakazu Hashimoto, Tatsuya Takemoto · Scientific Reports · 2015 · 319 citations · Full text

Mutant Mice, Off-target Effect, Functional Genomics +15

Tbx6-dependent Sox2 regulation determines neural or mesodermal fate in axial stem cells

Tatsuya Takemoto, Masanori Uchikawa, Megumi Yoshida et al. · Nature · 2011 · 273 citations

Developmental Biology, Axial Stem Cells, Medicine +9

Electroporation of Cas9 protein/sgRNA into early pronuclear zygotes generates non-mosaic mutants in the mouse

Masakazu Hashimoto, Yukiko Yamashita, Tatsuya Takemoto · Developmental Biology · 2016 · 228 citations

Rna Processing, Cas9 Protein/sgrna, Genetics +9