Ross Blundell

Characterization of the Complete Uric Acid Degradation Pathway in the Fungal Pathogen Cryptococcus neoformans

I. Russel Lee, Liting Yang, Gaseene Sebetso et al. · PLoS ONE · 2013 · 59 citations · Full text

Biochemistry, Uric Acid Utilization, Fungal Cell Biology +11

Convergent microevolution of Cryptococcus neoformans hypervirulence in the laboratory and the clinic

Samantha D. M. Arras, Kate L. Ormerod, Paige E. Erpf et al. · Scientific Reports · 2017 · 48 citations · Full text

Pathogenic Microbiology, Cryptococcus Neoformans Hypervirulence, Microbial Pathogens +23

Antifungal benzo[b]thiophene 1,1-dioxide IMPDH inhibitors exhibit pan-assay interference (PAINS) profiles

K. Lalith Kumar, Mark S. Butler, Emily Furlong et al. · Bioorganic & Medicinal Chemistry · 2018 · 22 citations · Full text

Inhibitory Activity, Medicinal Chemistry, Pharmaceutical Science +11

Disruption of de Novo Adenosine Triphosphate (ATP) Biosynthesis Abolishes Virulence in <i>Cryptococcus neoformans</i>

Ross Blundell, Simon J. Williams, Samantha D. M. Arras et al. · ACS Infectious Diseases · 2016 · 21 citations

Crystal Structure, Bacteriology, Molecular Biology +19

Cryptococcus neoformans ADS lyase is an enzyme essential for virulence whose crystal structure reveals features exploitable in antifungal drug design

Jessica L. Chitty, Kirsten L. Blake, Ross Blundell et al. · Journal of Biological Chemistry · 2017 · 16 citations · Full text