Thomas R. OʼBrien

A variant upstream of IFNL3 (IL28B) creating a new interferon gene IFNL4 is associated with impaired clearance of hepatitis C virus

Ludmila Prokunina‐Olsson, Brian Muchmore, Wei Tang et al. · Nature Genetics · 2013 · 911 citations · Full text

Impaired Clearance, Molecular Virology, Autoimmune Disease +10

Contrasting Genetic Influence of <i>CCR2</i> and <i>CCR5</i> Variants on HIV-1 Infection and Disease Progression

Michael W. Smith, Michael Dean, Mary Carrington et al. · Science · 1997 · 890 citations

Genetic Restriction of AIDS Pathogenesis by an SDF-1 Chemokine Gene Variant

Cheryl A. Winkler, William S. Modi, Michael W. Smith et al. · Science · 1998 · 724 citations

Immunodeficiencies, Immunology, Pathology +17

Relative resistance to HIV–1 infection of CD4 lymphocytes from persons who remain uninfected despite multiple high–risk sexual exposures

William A. Paxton, Scott R. Martin, Doris B. Tse et al. · Nature Medicine · 1996 · 651 citations

Sexual Health, Human Retrovirus, Relative Resistance +6

Impact of Classification of Hilar Cholangiocarcinomas (Klatskin Tumors) on the Incidence of Intra- and Extrahepatic Cholangiocarcinoma in the United States

Tania M. Welzel, Katherine A. McGlynn, Ann W. Hsing et al. · JNCI Journal of the National Cancer Institute · 2006 · 369 citations · Full text

Surgical Oncology, Epidemiology Of Cancer, Gastroenterology +22