Predicting population coverage of T-cell epitope-based diagnostics and vaccines

Huynh‐Hoa Bui, John Sidney, Kenny Dinh, +3

BMC Bioinformatics

The relationship between class I binding affinity and immunogenicity of potential cytotoxic T cell epitopes.

Alessandro Sette, Antonella Vitiello, B Reherman, +14

The Journal of Immunology

HistocompatibilityHla ImmunogeneticsImmunologyImmunodominanceAntigen Processing +15

Cutting Edge: The Conversion of Arginine to Citrulline Allows for a High-Affinity Peptide Interaction with the Rheumatoid Arthritis-Associated HLA-DRB1*0401 MHC Class II Molecule

Jonathan A. Hill, Scott Southwood, Alessandro Sette, +3

The Journal of Immunology

Several Common HLA-DR Types Share Largely Overlapping Peptide Binding Repertoires

Scott Southwood, John Sidney, Akihiro Kondo, +7

The Journal of Immunology

HistocompatibilityHlaMhc PolymorphismPeptide EngineeringHla Immunogenetics +24

Improved induction of melanoma-reactive CTL with peptides from the melanoma antigen gp100 modified at HLA-A*0201-binding residues

Maria R. Parkhurst, Michael L. Salgaller, Scott Southwood, +4

The Journal of Immunology

Recognition of multiple epitopes in the human melanoma antigen gp100 by tumor-infiltrating T lymphocytes associated with in vivo tumor regression.

Yutaka Kawakami, S Eliyahu, Cheryl Jennings, +7

The Journal of Immunology

ImmunologyPathologyAntigen ProcessingImmunotherapyVivo Tumor Regression +16

Development of high potency universal DR-restricted helper epitopes by modification of high affinity DR-blocking peptides

Jeff Alexander, John Sidney, Scott Southwood, +8

Immunity

Peptide LibraryPeptide EngineeringImmunologyPeptide TherapeuticAntigen Processing +5

Drug hypersensitivity caused by alteration of the MHC-presented self-peptide repertoire

David A. Ostrov, Barry J. Grant, Y.A. Pompeu, +19

Proceedings of the National Academy of Sciences

Adaptive Immune SystemImmunologyPathologyImmunodominanceImmunologic Mechanism +16

Altered peptide ligands can control CD4 T lymphocyte differentiation in vivo.

Christiane Pfeiffer, Judith Stein, Scott Southwood, +3

The Journal of Experimental Medicine

Lymphocyte DevelopmentAdaptive Immune SystemT-regulatory CellImmunologyImmunologic Mechanism +16

Immunological significance of cytotoxic T lymphocyte epitope variants in patients chronically infected by the hepatitis C virus.

Kyong‐Mi Chang, Barbara Rehermann, John G. McHutchison, +4

Journal of Clinical Investigation

Hepatitis C VirusImmunologyPathologyAntigen ProcessingImmune System +18