Treatment of Children and Adolescents With Metastatic Medulloblastoma and Prognostic Relevance of Clinical and Biologic Parameters

André O. von Bueren, Rolf‐Dieter Kortmann, Katja von Hoff, +23

Journal of Clinical Oncology

Pediatric Brain TumorsCancer ManagementSurgerySubgroup StatusNeuro-oncology +17

Prognostic significance of clinical, histopathological, and molecular characteristics of medulloblastomas in the prospective HIT2000 multicenter clinical trial cohort

Torsten Pietsch, René Schmidt, Marc Remke, +21

Acta Neuropathologica

Prognostic effect of whole chromosomal aberration signatures in standard-risk, non-WNT/non-SHH medulloblastoma: a retrospective, molecular analysis of the HIT-SIOP PNET 4 trial

Tobias Goschzik, Ed C. Schwalbe, Debbie Hicks, +8

The Lancet Oncology

Genomic Alterations of Adamantinomatous and Papillary Craniopharyngioma

Tobias Goschzik, Marco Gessi, Verena Dreschmann, +8

Journal of Neuropathology & Experimental Neurology

Molecular Diagnostic TechniquesMip DataMedicineGeneticsGenetic Disorder +13

<i>FGFR1</i>Mutations in Rosette-Forming Glioneuronal Tumors of the Fourth Ventricle

Marco Gessi, Yasmin Abdel Moneim, Jennifer Hammes, +5

Journal of Neuropathology & Experimental Neurology

Neuro-oncologyDevelopmental BiologyRosette-forming Glioneuronal TumorsGliomaReceptor Tyrosine Kinase +12

<i>PTEN</i>Mutations and Activation of the PI3K/Akt/mTOR Signaling Pathway in Papillary Tumors of the Pineal Region

Tobias Goschzik, Marco Gessi, Dorota Denkhaus, +1

Journal of Neuropathology & Experimental Neurology

CytogeneticsGeneticsPi3k/akt/mtor Signaling PathwayPathologyDisease Gene Identification +22

Molecular stratification of medulloblastoma: comparison of histological and genetic methods to detect <scp>Wnt</scp> activated tumours

Tobias Goschzik, Anja zur Mühlen, Glen Kristiansen, +7

Neuropathology and Applied Neurobiology

Minimal methylation classifier (MIMIC): A novel method for derivation and rapid diagnostic detection of disease-associated DNA methylation signatures

Ed C. Schwalbe, Debbie Hicks, Gholamreza Rafiee, +21

Scientific Reports

Genetic alterations of TP53 and OTX2 indicate increased risk of relapse in WNT medulloblastomas

Tobias Goschzik, Martin Mynarek, Evelyn Doerner, +11

Acta Neuropathologica

Identification of low and very high-risk patients with non-WNT/non-SHH medulloblastoma by improved clinico-molecular stratification of the HIT2000 and I-HIT-MED cohorts

Martin Mynarek, Denise Obrecht, Martin Sill, +21

Acta Neuropathologica