Philip J. Pye

A New Planar Chiral Bisphosphine Ligand for Asymmetric Catalysis:  Highly Enantioselective Hydrogenations under Mild Conditions

Philip J. Pye, Kai Rossen, Robert A. Reamer et al. · Journal of the American Chemical Society · 1997 · 368 citations

Engineering, Mild Conditions, Altmetric Attention Score +16

Efficient Synthesis of NK₁ Receptor Antagonist Aprepitant Using a Crystallization-Induced Diastereoselective Transformation

Karel M. J. Brands, Joseph F. Payack, Jonathan D. Rosen et al. · Journal of the American Chemical Society · 2003 · 156 citations

Medicinal Chemistry, Biochemistry, Functional Selectivity +14

Kinetic Resolution of <i>rac</i>-4,12-Dibromo[2.2]paracyclophane in a Palladium [2.2]PHANEPHOS Catalyzed Amination

Kai Rossen, Philip J. Pye, Ashok Maliakal et al. · The Journal of Organic Chemistry · 1997 · 139 citations

Chemical Engineering, Cross-coupling Reaction, Engineering +11

[2.2]PHANEPHOS-Ruthenium(II) complexes: Highly active asymmetric catalysts for the hydrogenation of β-ketoesters

Philip J. Pye, Kai Rossen, Robert A. Reamer et al. · Tetrahedron Letters · 1998 · 112 citations

Inorganic Chemistry, Chemical Engineering, Engineering +5

An efficient asymmetric hydrogenation approach to the synthesis of the Crixivan® piperazine intermediate

Kai Rossen, Philip J. Pye, Lisa DiMichele et al. · Tetrahedron Letters · 1998 · 103 citations

Engineering, Crixivan® Piperazine Intermediate, Organic Chemistry +6