Laura J. Lemieux

Arresting amyloidosis in vivo using small-molecule anionic sulphonates or sulphates: implications for Alzheimer's disease

Robert Kisilevsky, Laura J. Lemieux, Paul E. Fraser et al. · Nature Medicine · 1995 · 360 citations

Alzheimer's Disease, Biochemistry, Medicine +8

The sequence of the cyo operon indicates substantial structural similarities between the cytochrome o ubiquinol oxidase of Escherichia coli and the aa3-type family of cytochrome c oxidases.

V Chepuri, Laura J. Lemieux, D C Au et al. · Journal of Biological Chemistry · 1990 · 237 citations · Full text

Biochemistry, Bioelectrochemistry, Bioenergetics +12

Restoration of a lost metal-binding site: construction of two different copper sites into a subunit of the E. coli cytochrome o quinol oxidase complex.

John van der Oost, Pekka Lappalainen, Laura J. Lemieux et al. · The EMBO Journal · 1992 · 152 citations · Full text

E. Coli, Biochemistry, Bioelectrochemistry +10

Determination of the ligands of the low spin heme of the cytochrome o ubiquinol oxidase complex using site-directed mutagenesis.

Laura J. Lemieux, Melissa W. Calhoun, Jeffrey W. Thomas et al. · Journal of Biological Chemistry · 1992 · 111 citations · Full text

Molecular Biology, Escherichia Coli, Chemical Biology +18

Site-directed mutagenesis of highly conserved residues in helix VIII of subunit I of the cytochrome bo ubiquinol oxidase from Escherichia coli: An amphipathic transmembrane helix that may be important in conveying protons to the binuclear center

Jeffrey W. Thomas, Laura J. Lemieux, James O. Alben et al. · Biochemistry · 1993 · 53 citations