A DHODH inhibitor increases p53 synthesis and enhances tumor cell killing by p53 degradation blockage

Marcus J.G.W. Ladds, Ingeborg M.M. van Leeuwen, Catherine J. Drummond, +42

Nature Communications

3-Oxoisoindoline-1-carboxamides: Potent, State-Dependent Blockers of Voltage-Gated Sodium Channel Na_V1.7 with Efficacy in Rat Pain Models

István Macsári, Yevgeni Besidski, Gabor Csjernyik, +12

Journal of Medicinal Chemistry

Pain MedicineState-dependent BlockersOxoisoindoline CoreAnesthetic MechanismMolecular Pain +23

Formation of Hydroxyl Spin Adducts via Nucleophilic Addition--Oxidation to 5,5-Dimethyl-1-pyrroline N-Oxide (DMPO).

Lennart Eberson, Balin Balinov, Gunnar Hagelin, +8

Acta chemica Scandinavica/Acta chemica Scandinavica. B, Organic chemistry and biochemistry/Acta chemica Scandinavica. A, Physical and inorganic chemistry/Acta chemica Scandinavica. Series B. Organic chemistry and biochemistry/Acta chemica Scandinavica. Series A, Physical and inorganic chemistry

BiochemistryNatural SciencesNucleophilic Addition5,5-Dimethyl-1-pyrroline N-oxideOrganic Chemistry +2

Comprehensive Summaries of Uppsala Dissertations from the Faculty of Science and Technology 605

Ulrika Yngve

Related MaterialMethodological DevelopmentUppsala DissertationsComprehensive SummariesHuman-computer Interaction +4

Distribution of 76Br-labeled antisense oligonucleotides of different length determined ex vivo in rats

Feng Wu, Ulrika Yngve, Elisabeth Hedberg, +5

European Journal of Pharmaceutical Sciences

76Br-labeled Antisense OligonucleotidesNatural SciencesImmunologyOligonucleotideMolecular Biology +5

Brain mGluR5 in mice with amyloid beta pathology studied with in vivo [11C]ABP688 PET imaging and ex vivo immunoblotting

Xiaotian T. Fang, Jonas Eriksson, Gunnar Antoni, +5

Neuropharmacology

Microwave accelerated ⁶⁸Ga‐labelling of oligonucleotides

Irina Velikyan, Gábor Lendvai, Maria Välilä, +4

Journal of Labelled Compounds and Radiopharmaceuticals

EngineeringChemical ModificationMolecular BiologyNucleic Acid BiomarkersSense Oligonucleotide +16

Sex Pheromone of the Pine Sawfly, Macrodiprion nemoralis. Stereoselective Synthesis of the Sixteen Stereoisomers of 3,7,9-Trimethyl-2-tridecyl Acetate.

Staffan Karlsson, Erik Hedenström, Luís Lezama, +8

Acta chemica Scandinavica/Acta chemica Scandinavica. B, Organic chemistry and biochemistry/Acta chemica Scandinavica. A, Physical and inorganic chemistry/Acta chemica Scandinavica. Series B. Organic chemistry and biochemistry/Acta chemica Scandinavica. Series A, Physical and inorganic chemistry

BiologyPheromone BiochemistryBioorganic ChemistryNatural SciencesPine Sawfly +10

Optimization of Tetrahydroindazoles as Inhibitors of Human Dihydroorotate Dehydrogenase and Evaluation of Their Activity and In Vitro Metabolic Stability

Gergana Popova, Marcus J.G.W. Ladds, Lars Johansson, +11

Journal of Medicinal Chemistry

Synthesis of N-Succinimidyl 4-[76Br]Bromobenzoate and its Use in Conjugation Labelling of Macromolecules.

Ulrika Yngve, Elisabeth Hedberg, Anna Lövqvist, +8

Acta chemica Scandinavica/Acta chemica Scandinavica. B, Organic chemistry and biochemistry/Acta chemica Scandinavica. A, Physical and inorganic chemistry/Acta chemica Scandinavica. Series B. Organic chemistry and biochemistry/Acta chemica Scandinavica. Series A, Physical and inorganic chemistry

Combinatorial ChemistryDiversity Oriented SynthesisConjugation LabellingBr-76 RadiobrominationBiochemistry +11