SPG7 Is an Essential and Conserved Component of the Mitochondrial Permeability Transition Pore

Santhanam Shanmughapriya, Sudarsan Rajan, Nicholas E. Hoffman, +18

Molecular Cell

BiologyBiochemistryMitochondrial FunctionNatural SciencesMedicine +8

The actin cytoskeleton regulates exocytosis of all neutrophil granule subsets

Neelakshi R. Jog, Madhavi J. Rane, George Lominadze, +3

American Journal of Physiology-Cell Physiology

Protein SecretionM FmlpImmunologyPathologyCytoskeleton +16

Ca ²⁺ signals regulate mitochondrial metabolism by stimulating CREB-mediated expression of the mitochondrial Ca ²⁺ uniporter gene <i>MCU</i>

Santhanam Shanmughapriya, Sudarsan Rajan, Nicholas E. Hoffman, +14

Science Signaling

Requirement of FADD, NEMO, and BAX/BAK for Aberrant Mitochondrial Function in Tumor Necrosis Factor Alpha-Induced Necrosis

Krishna M. Irrinki, Karthik Mallilankaraman, Roshan J. Thapa, +9

Molecular and Cellular Biology

InflammationTnf-α-dependent NecroptosisMitophagyMitochondrial FunctionApoptosis +13

Comparison of Proteins Expressed on Secretory Vesicle Membranes and Plasma Membranes of Human Neutrophils

Silvia M. Uriarte, David W. Powell, Gregory C. Luerman, +5

The Journal of Immunology

Protein SecretionImmunologyMolecular BiologyPlasma MembranesCellular Physiology +24

Association of Epstein-Barr virus serological reactivation with transitioning to systemic lupus erythematosus in at-risk individuals

Neelakshi R. Jog, Kendra A. Young, Melissa E. Munroe, +12

Annals of the Rheumatic Diseases

Epstein Barr virus nuclear antigen 1 (EBNA-1) peptides recognized by adult multiple sclerosis patient sera induce neurologic symptoms in a murine model

Neelakshi R. Jog, Micah T. McClain, Latisha Heinlen, +7

Journal of Autoimmunity

Autoimmune DiseaseNeurological DisorderMedicineMurine ModelImmunology +9

Epstein Barr Virus Interleukin 10 Suppresses Anti-inflammatory Phenotype in Human Monocytes

Neelakshi R. Jog, Eliza F. Chakravarty, Joel M. Guthridge, +1

Frontiers in Immunology

Clinical ImmunologySuppresses Anti-inflammatory PhenotypeImmune RegulationImmunologyImmunologic Mechanism +15

Heat Shock Protein 27 Regulates Neutrophil Chemotaxis and Exocytosis through Two Independent Mechanisms

Neelakshi R. Jog, Venkatakrishna R. Jala, Richard A. Ward, +3

The Journal of Immunology

Poly(ADP-Ribose) Polymerase-1 Regulates the Progression of Autoimmune Nephritis in Males by Inducing Necrotic Cell Death and Modulating Inflammation

Neelakshi R. Jog, Joudy-Ann Dinnall, Stefania Gallucci, +2

The Journal of Immunology

Glomerular DiseaseRenal PathologyImmunologyRenal InflammationPathology +23