Roald A. Lambrechts

Extracellular 4′-phosphopantetheine is a source for intracellular coenzyme A synthesis

Balaji Srinivasan, Madina Baratashvili, Marianne van der Zwaag et al. · Nature Chemical Biology · 2015 · 130 citations

Life Sciences, Biochemistry, Molecular Biology +10

4′‐Phosphopantetheine corrects CoA, iron, and dopamine metabolic defects in mammalian models of PKAN

Suh Young Jeong, Penelope Hogarth, Andrew T. Placzek et al. · EMBO Molecular Medicine · 2019 · 81 citations · Full text

Life Sciences, Medicinal Chemistry, Neuroscience +8

CoA‐dependent activation of mitochondrial acyl carrier protein links four neurodegenerative diseases

Roald A. Lambrechts, Hein Schepers, Yi Yu et al. · EMBO Molecular Medicine · 2019 · 71 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +17

The efficacy of the modified Atkins diet in North Sea Progressive Myoclonus Epilepsy: an observational prospective open-label study

Martje E. van Egmond, Amerins Weijenberg, Margreet E. van Rijn et al. · Orphanet Journal of Rare Diseases · 2017 · 37 citations · Full text

Medicine, Nutritional Sciences, Pharmacotherapy +17

North Sea Progressive Myoclonus Epilepsy is Exacerbated by Heat, A Phenotype Primarily Associated with Affected Glia

Roald A. Lambrechts, Sjoukje S. Polet, Alejandra Hernandez Pichardo et al. · Neuroscience · 2019 · 13 citations · Full text

Medicine, Neurology, Neuroscience +10