Yongchuan Gu

Mechanism of Action and Preclinical Antitumor Activity of the Novel Hypoxia-Activated DNA Cross-Linking Agent PR-104

Adam V. Patterson, Dianne M. Ferry, Shelley J. Edmunds et al. · Clinical Cancer Research · 2007 · 243 citations · Full text

Phase I/II study of the hypoxia-activated prodrug PR104 in refractory/relapsed acute myeloid leukemia and acute lymphoblastic leukemia

Marina Konopleva, Peter F. Thall, Cecilia Arana Yi et al. · Haematologica · 2015 · 119 citations · Full text

Phase I/ii Study, Mixed-phenotype Acute Leukemia, Immunology +18

Hypoxia-Induced WSB1 Promotes the Metastatic Potential of Osteosarcoma Cells

Ji Cao, Yijie Wang, Rong Dong et al. · Cancer Research · 2015 · 79 citations

Identification of P450 Oxidoreductase as a Major Determinant of Sensitivity to Hypoxia-Activated Prodrugs

Francis W. Hunter, Richard J. Young, Zvi Shalev et al. · Cancer Research · 2015 · 79 citations

Lipid Peroxidation, P450 Oxidoreductase, Pharmacotherapy +18

Transport and Bioavailability Studies of Astragaloside IV, an Active Ingredient in <i>Radix Astragali</i>

Yongchuan Gu, Guangji Wang, Guoyu Pan et al. · Basic & Clinical Pharmacology & Toxicology · 2004 · 76 citations