Patrick Constantinescu

Protease‐activated alpha‐2‐macroglobulin can inhibit amyloid formation via two distinct mechanisms

Amy R. Wyatt, Patrick Constantinescu, Heath Ecroyd et al. · FEBS Letters · 2013 · 54 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +17

P2X7 receptor activation induces cell death and microparticle release in murine erythroleukemia cells

Patrick Constantinescu, Bin Wang, Kati Kovacevic et al. · Biochimica et Biophysica Acta (BBA) - Biomembranes · 2010 · 44 citations

Life Sciences, Cell Biology, Pharmacology +12

SerpinB2 (PAI-2) Modulates Proteostasis via Binding Misfolded Proteins and Promotion of Cytoprotective Inclusion Formation

Jodi Lee, Justin J. Yerbury, Natalie E. Farrawell et al. · PLoS ONE · 2015 · 41 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +13

Amorphous protein aggregates stimulate plasminogen activation, leading to release of cytotoxic fragments that are clients for extracellular chaperones

Patrick Constantinescu, Rebecca Brown, Amy R. Wyatt et al. · Journal of Biological Chemistry · 2017 · 30 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +17

Enhancing anti-tumor immunity of natural killer cells through targeting IL-15R signaling

Iva Nikolić, Joseph Cursons, Benjamin Shields et al. · Cancer Cell · 2025 · 24 citations

Life Sciences, Immunology, Oncology +15