Presence of<i>Epidermal Growth Factor Receptor</i>Gene T790M Mutation as a Minor Clone in Non–Small Cell Lung Cancer

Michio Inukai, Shinichi Toyooka, Sachio Ito, +10

Cancer Research

Significant correlation of the SCN1A mutations and severe myoclonic epilepsy in infancy

Iori Ohmori, Mamoru Ouchida, Yoko Ohtsuka, +2

Biochemical and Biophysical Research Communications

Scn1a MutationsSignificant CorrelationNeurological DisorderGeneticsGenetic Disorder +7

Gene silencing of the tyrosine phosphatase SHP1 gene by aberrant methylation in leukemias/lymphomas.

Takashi Oka, Mamoru Ouchida, Maho Koyama, +12

PubMed

Epigenetic ChangeGeneticsMixed-phenotype Acute LeukemiaPathologyFunctional Loss +14

The EWS gene, involved in Ewing family of tumors, malignant melanoma of soft parts and desmoplastic small round cell tumors, codes for an RNA binding protein with novel regulatory domains.

Takatoshi Ohno, Mamoru Ouchida, Leo Lee, +3

PubMed

Detection of<i>EGFR</i>Gene Mutation in Lung Cancer by Mutant-Enriched Polymerase Chain Reaction Assay

Hiroaki Asano, Shinichi Toyooka, Masaki Tokumo, +12

Clinical Cancer Research

TLS/FUS fusion domain of TLS/FUS-erg chimeric protein resulting from the t(16;21) chromosomal translocation in human myeloid leukemia functions as a transcriptional activation domain.

D.D.K. Prasad, Mamoru Ouchida, Leo Lee, +2

PubMed

Genomic structure of the human ING1 gene and tumor-specific mutations detected in head and neck squamous cell carcinomas.

Mehmet Gündüz, Mamoru Ouchida, Kunihiro Fukushima, +5

PubMed

Mrna VariantsIng1 GeneGeneticsPathologyTumor-specific Mutations +15

<i>MET</i> gene amplification or <i>EGFR</i> mutation activate MET in lung cancers untreated with EGFR tyrosine kinase inhibitors

Takafumi Kubo, Hiromasa Yamamoto, William W. Lockwood, +16

International Journal of Cancer

EngineeringMet ProteinPathologyCancer BiologyTumor Biology +15

Loss of tumorigenicity of Ewing's sarcoma cells expressing antisense RNA to EWS-fusion transcripts.

Mamoru Ouchida, Takatoshi Ohno, Yasuo Fujimura, +2

PubMed

Allelic loss and reduced expression of the ING3, a candidate tumor suppressor gene at 7q31, in human head and neck cancers

Mehmet Gündüz, Mamoru Ouchida, Kunihiro Fukushima, +6

Oncogene

GeneticsPathologyPhd DomainCancer BiologyTumor Biology +16