MTOR-independent, autophagic enhancer trehalose prolongs motor neuron survival and ameliorates the autophagic flux defect in a mouse model of amyotrophic lateral sclerosis

Xiaojie Zhang, Sheng Chen, Lin Song, +4

Autophagy

MitophagyCell DeathCellular NeurobiologyCell AutophagySelective Motor +16

Hypoxia increases Aβ generation by altering β- and γ-cleavage of APP

Liang Li, Xiaojie Zhang, Dehua Yang, +2

Neurobiology of Aging

Molecular NeuroscienceSignal TransductionAβ GenerationPhysiologyHypoxia (Medicine) +8

In-cell architecture of the nuclear pore and snapshots of its turnover

Matteo Allegretti, Christian E. Zimmerli, Vasileios Rantos, +15

Nature

In-cell ArchitectureNuclear StructureCell OrganelleNatural SciencesNuclear Pore +8

Enhanced salinomycin production by adjusting the supply of polyketide extender units in Streptomyces albus

Chenyang Lu, Xiaojie Zhang, Ming Jiang, +1

Metabolic Engineering

Enhanced Salinomycin ProductionEngineeringAntimicrobial SusceptibilityAntibiotic AdjuvantBiochemical Engineering +5

Thrombospondin 2 Potentiates Notch3/Jagged1 Signaling

He Meng, Xiaojie Zhang, Kurt D. Hankenson, +1

Journal of Biological Chemistry

ImmunologyThrombosisSignaling PathwayCell RegulationReceptor Tyrosine Kinase +14

Biochemical Characterization and Cellular Effects of CADASIL Mutants of NOTCH3

He Meng, Xiaojie Zhang, Genggeng Yu, +4

PLoS ONE

Natural SciencesAutophagyGene ExpressionMolecular BiologyElevated Notch3 +10

Verapamil Ameliorates Motor Neuron Degeneration and Improves Lifespan in the SOD1G93A Mouse Model of ALS by Enhancing Autophagic Flux

Xiaojie Zhang, Sheng Chen, Kaili Lu, +7

Aging and Disease

Autophagic FluxSynaptic TransmissionAls Mouse ModelCell DeathCellular Neurobiology +26

Expression of apoptosis-associated microRNAs in ethanol-induced acute gastric mucosal injury via JNK pathway

Xiu‐Ju Luo, Bin Liu, Zhong Dai, +6

Alcohol

InflammationApoptosisGastroenterologyCell DeathPathology +10

Storm surge risk assessment method for a coastal county in China: case study of Jinshan District, Shanghai

Xianwu Shi, Jufei Qiu, Bingrui Chen, +4

Stochastic Environmental Research and Risk Assessment

MeteorologyJinshan DistrictCoastal CountyEngineeringStorm Surge +10

Transcriptomic screening for cyclotides and other cysteine-rich proteins in the metallophyte Viola baoshanensis

Jun Zhang, Jintian Li, Zebo Huang, +7

Journal of Plant Physiology

BiologyPlant Molecular BiologyFunctional GenomicsMetallophyte Viola BaoshanensisGenetics +9