Evolutionary history of metastatic breast cancer reveals minimal seeding from axillary lymph nodes

Ikram Ullah, Govindasamy-Muralidharan Karthik, Amjad Alkodsi, +8

Journal of Clinical Investigation

Molecular features encoded in the ctDNA reveal heterogeneity and predict outcome in high-risk aggressive B-cell lymphoma

Leo Meriranta, Amjad Alkodsi, Annika Pasanen, +17

Blood

A Functional Homologous Recombination Assay Predicts Primary Chemotherapy Response and Long-Term Survival in Ovarian Cancer Patients

Manuela Tumiati, Sakari Hietanen, Johanna Hynninen, +16

Clinical Cancer Research

Impact of constitutional TET2 haploinsufficiency on molecular and clinical phenotype in humans

Eevi Kaasinen, Outi Kuismin, Kristiina Rajamäki, +32

Nature Communications

Genetic predisposition to uterine leiomyoma is determined by loci for genitourinary development and genome stability

Niko Välimäki, Heli Kuisma, Annukka Pasanen, +15

eLife

Comparative analysis of methods for identifying somatic copy number alterations from deep sequencing data

Amjad Alkodsi, Riku Louhimo, Sampsa Hautaniemi

Briefings in Bioinformatics

EngineeringGeneticsPathologyGenomicsScna Detection Algorithms +20

Anduril 2: upgraded large-scale data integration framework

Alejandra Cervera, Ville Rantanen, Kristian Ovaska, +13

Bioinformatics

PRISM: recovering cell-type-specific expression profiles from individual composite RNA-seq samples

Antti Häkkinen, Kaiyang Zhang, Amjad Alkodsi, +13

Bioinformatics

Molecular background delineates outcome of double protein expressor diffuse large B-cell lymphoma

Leo Meriranta, Annika Pasanen, Amjad Alkodsi, +3

Blood Advances

Distinct subtypes of diffuse large B-cell lymphoma defined by hypermutated genes

Amjad Alkodsi, Alejandra Cervera, Kaiyang Zhang, +8

Leukemia

Hematological MalignancyLymphoid NeoplasiaImmunologyHematologyPathology +6