Darwin W. Reed

High-level semi-synthetic production of the potent antimalarial artemisinin

Christopher J. Paddon, Patrick J. Westfall, Douglas J. Pitera et al. · Nature · 2013 · 2.1K citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +12

<i>Artemisia annua</i> L. (Asteraceae) trichome‐specific cDNAs reveal CYP71AV1, a cytochrome P450 with a key role in the biosynthesis of the antimalarial sesquiterpene lactone artemisinin

Keat H. Teoh, Devin R. Polichuk, Darwin W. Reed et al. · FEBS Letters · 2006 · 412 citations · Full text

Life Sciences, Plant Biology, Plant Sciences +17

The Molecular Cloning of Artemisinic Aldehyde Δ11(13) Reductase and Its Role in Glandular Trichome-dependent Biosynthesis of Artemisinin in Artemisia annua

Yansheng Zhang, Keat H. Teoh, Darwin W. Reed et al. · Journal of Biological Chemistry · 2008 · 305 citations · Full text

Life Sciences, Biochemistry, Plant Sciences +11

Alteration of Seed Fatty Acid Composition by an Ethyl Methanesulfonate-Induced Mutation in Arabidopsis thaliana Affecting Diacylglycerol Acyltransferase Activity

Vesna Katavić, Darwin W. Reed, David C. Taylor et al. · PLANT PHYSIOLOGY · 1995 · 284 citations · Full text

Life Sciences, Plant Biology, Plant Sciences +17

Molecular cloning of an aldehyde dehydrogenase implicated in artemisinin biosynthesis in <i>Artemisia annua</i>This paper is one of a selection of papers published in a Special Issue from the National Research Council of Canada – Plant Biotechnology Institute.

Keat H. Teoh, Devin R. Polichuk, Darwin W. Reed et al. · Botany · 2009 · 257 citations · Full text

Life Sciences, Molecular Biology, Plant Biology +16