Ira J. Smith

Calpain activation causes a proteasome‐dependent increase in protein degradation and inhibits the Akt signalling pathway in rat diaphragm muscle

Ira J. Smith, Stephen Dodd · Experimental Physiology · 2007 · 117 citations

Muscle Function, Proteasome, Cytoskeleton +22

Sepsis increases the expression and activity of the transcription factor Forkhead Box O 1 (FOXO1) in skeletal muscle by a glucocorticoid-dependent mechanism

Ira J. Smith, Nima Alamdari, Patrick O’Neal et al. · The International Journal of Biochemistry & Cell Biology · 2010 · 85 citations · Full text

Inflammation, Transcriptional Regulation, Molecular Physiology +10

Sepsis and glucocorticoids upregulate p300 and downregulate HDAC6 expression and activity in skeletal muscle

Nima Alamdari, Ira J. Smith, Zaira Aversa et al. · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · 2010 · 55 citations · Full text

Muscle Function, Cell Death, Glucocorticoid +16

AMPK Activation through Mitochondrial Regulation Results in Increased Substrate Oxidation and Improved Metabolic Parameters in Models of Diabetes

Yonchu Jenkins, Tian‐Qiang Sun, Vadim Markovtsov et al. · PLoS ONE · 2013 · 53 citations · Full text

CALPAIN activity is increased in skeletal muscle from gastric cancer patients with no or minimal weight loss

Ira J. Smith, Zaira Aversa, Per‐Olof Hasselgren et al. · Muscle & Nerve · 2011 · 50 citations