Calpain activation causes a proteasome‐dependent increase in protein degradation and inhibits the Akt signalling pathway in rat diaphragm muscle

Ira J. Smith, Stephen Dodd

Experimental Physiology

Muscle FunctionProteasomeCytoskeletonCalpain ActivationSkeletal Muscle Atrophy +20

Sepsis increases the expression and activity of the transcription factor Forkhead Box O 1 (FOXO1) in skeletal muscle by a glucocorticoid-dependent mechanism

Ira J. Smith, Nima Alamdari, Patrick O’Neal, +3

The International Journal of Biochemistry & Cell Biology

InflammationTranscriptional RegulationMolecular PhysiologySkeletal MuscleDisease Pathophysiology +8

Sepsis and glucocorticoids upregulate p300 and downregulate HDAC6 expression and activity in skeletal muscle

Nima Alamdari, Ira J. Smith, Zaira Aversa, +1

American Journal of Physiology-Regulatory, Integrative and Comparative Physiology

Muscle FunctionCell DeathGlucocorticoidHdac ActivityCellular Physiology +14

AMPK Activation through Mitochondrial Regulation Results in Increased Substrate Oxidation and Improved Metabolic Parameters in Models of Diabetes

Yonchu Jenkins, Tian‐Qiang Sun, Vadim Markovtsov, +34

PLoS ONE

CALPAIN activity is increased in skeletal muscle from gastric cancer patients with no or minimal weight loss

Ira J. Smith, Zaira Aversa, Per‐Olof Hasselgren, +4

Muscle & Nerve

The JAK-STAT Pathway Is Critical in Ventilator-Induced Diaphragm Dysfunction

Huibin Tang, Ira J. Smith, Sabah N. A. Hussain, +9

Molecular Medicine

Inhibition of Janus kinase signaling during controlled mechanical ventilation prevents ventilation‐induced diaphragm dysfunction

Ira J. Smith, Guillermo Godinez, Baljit K. Singh, +30

The FASEB Journal

Exercise performance and peripheral vascular insufficiency improve with AMPK activation in high-fat diet-fed mice

Kristen A. Baltgalvis, Kathy White, Wei Li, +25

American Journal of Physiology-Heart and Circulatory Physiology

Sepsis and glucocorticoids downregulate the expression of the nuclear cofactor PGC-1β in skeletal muscle

Michael J. Menconi, Zoltàn Arany, Nima Alamdari, +6

American Journal of Physiology-Endocrinology and Metabolism

Cell DeathGlucocorticoidCellular PhysiologyMuscle AtrophyOxidative Stress +20

Sepsis downregulates myostatin mRNA levels without altering myostatin protein levels in skeletal muscle

Ira J. Smith, Zaira Aversa, Nima Alamdari, +2

Journal of Cellular Biochemistry