Giorgio Amendola

Development of Novel Peptide-Based Michael Acceptors Targeting Rhodesain and Falcipain-2 for the Treatment of Neglected Tropical Diseases (NTDs)

Santo Previti, Roberta Ettari, Sandro Cosconati et al. · Journal of Medicinal Chemistry · 2017 · 58 citations · Full text

Discovery of a Novel Chemotype of Histone Lysine Methyltransferase EHMT1/2 (GLP/G9a) Inhibitors: Rational Design, Synthesis, Biological Evaluation, and Co-crystal Structure

Ciro Milite, Alessandra Feoli, J.R. Horton et al. · Journal of Medicinal Chemistry · 2019 · 56 citations · Full text

Lead Discovery of SARS-CoV-2 Main Protease Inhibitors through Covalent Docking-Based Virtual Screening

Giorgio Amendola, Roberta Ettari, Santo Previti et al. · Journal of Chemical Information and Modeling · 2021 · 54 citations

PyRMD: A New Fully Automated AI-Powered Ligand-Based Virtual Screening Tool

Giorgio Amendola, Sandro Cosconati · Journal of Chemical Information and Modeling · 2021 · 54 citations · Full text

Artificial Intelligence, New Ligands, Hit Identification +21

Novel 2-substituted-benzimidazole-6-sulfonamides as carbonic anhydrase inhibitors: synthesis, biological evaluation against isoforms I, II, IX and XII and molecular docking studies

Ciro Milite, Giorgio Amendola, Alessio Nocentini et al. · Journal of Enzyme Inhibition and Medicinal Chemistry · 2019 · 39 citations · Full text

Combinatorial Chemistry, Bioorganic Chemistry, Novel 2-Substituted-benzimidazole-6-sulfonamides +19