Lifen Gong

Captopril alleviates epilepsy and cognitive impairment by attenuation of C3-mediated inflammation and synaptic phagocytosis

Xinyan Dong, Jianchen Fan, Donghui Lin et al. · Journal of Neuroinflammation · 2022 · 72 citations · Full text

Medicine, Neuroscience, Pharmacology +17

TRPM2 contributes to neuroinflammation and cognitive deficits in a cuprizone-induced multiple sclerosis model via NLRP3 inflammasome

Yu Shao, Chen Chen, Tao Zhu et al. · Neurobiology of Disease · 2021 · 46 citations · Full text

Life Sciences, Neurology, Neuroscience +17

Transient receptor potential melastatin 2 contributes to neuroinflammation and negatively regulates cognitive outcomes in a pilocarpine-induced mouse model of epilepsy

Hui Hu, Tao Zhu, Lifen Gong et al. · International Immunopharmacology · 2020 · 43 citations

Medicine, Neuroscience, Pharmacology +14

Preferential pruning of inhibitory synapses by microglia contributes to alteration of the balance between excitatory and inhibitory synapses in the hippocampus in temporal lobe epilepsy

Jianchen Fan, Xinyan Dong, Yejiao Tang et al. · CNS Neuroscience & Therapeutics · 2023 · 35 citations · Full text

Life Sciences, Neurobiology, Neuroscience +17

Trpm2 deficiency in microglia attenuates neuroinflammation during epileptogenesis by upregulating autophagy via the AMPK/mTOR pathway

Chen Chen, Tao Zhu, Lifen Gong et al. · Neurobiology of Disease · 2023 · 29 citations · Full text

Life Sciences, Neurobiology, Neuroscience +17