Lubna Ghanem

On-demand male contraception via acute inhibition of soluble adenylyl cyclase

Melanie Balbach, Thomas Rossetti, Jacob Ferreira et al. · Nature Communications · 2023 · 72 citations · Full text

Soluble adenylyl cyclase inhibition prevents human sperm functions essential for fertilization

Melanie Balbach, Lubna Ghanem, Thomas Rossetti et al. · Molecular Human Reproduction · 2021 · 51 citations · Full text

Capacitation induces changes in metabolic pathways supporting motility of epididymal and ejaculated sperm

Melanie Balbach, Lubna Ghanem, Sara Violante et al. · Frontiers in Cell and Developmental Biology · 2023 · 32 citations · Full text

Design, Synthesis, and Pharmacological Evaluation of Second-Generation Soluble Adenylyl Cyclase (sAC, ADCY10) Inhibitors with Slow Dissociation Rates

Michael Miller, Thomas Rossetti, Jacob Ferreira et al. · Journal of Medicinal Chemistry · 2022 · 21 citations · Full text

Assessing potency and binding kinetics of soluble adenylyl cyclase (sAC) inhibitors to maximize therapeutic potential

Thomas Rossetti, Jacob Ferreira, Lubna Ghanem et al. · Frontiers in Physiology · 2022 · 11 citations · Full text