An optimized ionizable cationic lipid for brain tumor-targeted siRNA delivery and glioblastoma immunotherapy

Shuhan Liu, Ji Liu, Haisong Li, +13

Biomaterials

Lipid PreparationNanomedicineCell-based Drug DeliveryEngineeringGlioma +6

Intratumoral delivery of CCL25 enhances immunotherapy against triple-negative breast cancer by recruiting CCR9 ⁺ T cells

Hongmei Chen, Xiuxiu Cong, Chenxi Wu, +16

Science Advances

Photodynamic therapy produces enhanced efficacy of antitumor immunotherapy by simultaneously inducing intratumoral release of sorafenib

Xu Sun, Ziyang Cao, Kuirong Mao, +10

Biomaterials

Antitumor ImmunotherapyPhotodynamic TherapyMedicineImmunologyPhototoxicity +7

Cationic Liposome/DNA Complexes Mediate Antitumor Immunotherapy by Promoting Immunogenic Tumor Cell Death and Dendritic Cell Activation

Xiuxiu Cong, Huimin Tian, Shuhan Liu, +12

ACS Applied Materials & Interfaces

Intratumoral delivery of M-CSF by calcium crosslinked polymer micelles enhances cancer immunotherapy

Kuirong Mao, Xiuxiu Cong, Liangzhu Feng, +7

Biomaterials Science

Intratumoral DeliveryEngineeringImmunologyBiomedical EngineeringImmunotherapy +15

Maleimide as the PEG end-group promotes macrophage-targeted drug delivery of PEGylated nanoparticles in vivo by enhancing interaction with circulating erythrocytes

Xin Wang, Xiandi Meng, Kuirong Mao, +10

Biomaterials

NanoparticlesNanomedicineCell-based Drug DeliveryDrug TargetingEngineering +4

Nanoparticle delivery of <i>CD40</i> siRNA suppresses alloimmune responses by inhibiting activation and differentiation of DCs and macrophages

Jialiang Wang, Kuirong Mao, Xiuxiu Cong, +5

Science Advances

The influence of tumor-induced immune dysfunction on the immune cell distribution of gold nanoparticles in vivo

Chenxi Wu, Hongmei Chen, Xuan Wu, +6

Biomaterials Science

NanoparticlesNanomedicineImmune Cell DistributionEngineeringTumor-induced Immune Dysfunction +13

Lipid-mediated delivery of CD47 siRNA aids JQ1 in ensuring simultaneous downregulation of PD-L1 and CD47 and improves antitumor immunotherapy efficacy

Yong Li, Xianying Meng, Guang Chen, +12

Biomaterials Science

Optimized lipid nanoparticles enable effective CRISPR/Cas9-mediated gene editing in dendritic cells for enhanced immunotherapy

Kuirong Mao, Huizhu Tan, Xiuxiu Cong, +13

Acta Pharmaceutica Sinica B