Helen Benson

Development and Scale-up of a Biocatalytic Process To Form a Chiral Sulfoxide

William R. F. Goundry, Bradley Adams, Helen Benson et al. · Organic Process Research & Development · 2017 · 62 citations

Engineering, Biotechnology, Chemical Engineering +17

Development of the Convergent, Kilogram-Scale Synthesis of an Antibacterial Clinical Candidate Using Enantioselective Hydrogenation

Helen Benson, Karen Bones, Gwydion Churchill et al. · Organic Process Research & Development · 2020 · 24 citations

Pharmacy, Chemistry, Medicinal Chemistry +13

Development and Manufacture of a Curtius Rearrangement Using Continuous Flow towards the Large-Scale Manufacture of AZD7648

Carl J. Mallia, Niall G. McCreanor, Daniel H. Legg et al. · Organic Process Research & Development · 2022 · 19 citations

Engineering, Chemical Engineering, Chemistry +14

Multikilogram-Scale Preparation of AZD4635 via C–H Borylation and Bromination: The Corrosion of Tantalum by a Bromine/Methanol Mixture

James J. Douglas, Bradley Adams, Helen Benson et al. · Organic Process Research & Development · 2018 · 18 citations

Natural Sciences, Chemistry, Materials Science +14

From Milligram to Kilogram Manufacture of AZD4573: Making It Possible by Application of Enzyme-, Iridium-, and Palladium-Catalyzed Key Transformations

Staffan Karlsson, Helen Benson, Calum Cook et al. · Organic Process Research & Development · 2021 · 12 citations

Pharmacy, Medicinal Chemistry, Biocatalysis +9