Lymphopenia in the BB Rat Model of Type 1 Diabetes is Due to a Mutation in a Novel Immune-Associated Nucleotide (<i>Ian</i>)-Related Gene

Armand J. MacMurray, Daniel H. Moralejo, Anne E. Kwitek, +17

Genome Research

Prevalence of autoantibodies to the 65- and 67-kD isoforms of glutamate decarboxylase in insulin-dependent diabetes mellitus.

Josef Amann, Ludwig Mauch, Heinz Haubruck, +6

Journal of Clinical Investigation

Autoimmune DiseaseBiochemistryInsulin-dependent Diabetes MellitusSera Gad65Iddm Antibodies +13

Recombinant human platelet-activating factor acetylhydrolase reduces the frequency of diabetes in the diabetes-prone BB rat.

E S Lee, Jimmy J. Jiang, Greg Sund, +7

Diabetes

ImmunologyPaf LevelsPaf InhibitorsInsulin SignalingInflammation +17

Association between Antibodies to the MR 67,000 Isoform of Glutamate Decarboxylase (GAD) and Type 1 (Insulin-Dependent) Diabetes Mellitus with Coexisting Autoimmune Polyendocrine Syndrome Type II

Sabine Bieg, Nadja Yassin, Ludwig Mauch, +3

Autoimmunity

Genetic isolation of iddm 1 on Chromosome 4 in the BioBreeding (BB) rat

Sabine Bieg, George Koike, Jianming Jiang, +6

Mammalian Genome

BiologyGenetic IsolationGenetic DisorderGeneticsMolecular Genetics +7

Circulating intercellular adhesion molecule 1 as a new activity marker in patients with systemic lupus erythematosus

Elisabeth Kling, Sabine Bieg, Michael Boehme, +1

Journal of Molecular Medicine

InflammationNew Activity MarkerAutoimmune DiseaseSystemic Lupus ErythematosusLupus +11

BB rat diabetes susceptibility and body weight regulation genes colocalize on Chromosome 2

Lindy S. Klaff, George Koike, Yanling Wang, +4

Mammalian Genome

ObesityMetabolic SyndromeGenetic DeterminantDevelopmental BiologyBb Rat +8

A multiplicity of protein antigens in subcellular fractions of rat insulinoma tissue are able to stimulate T cells obtained from non-obese diabetic mice

Sabine Bieg, E M Bailyes, N. Yassin, +5

Diabetologia

Autoimmune DiseaseProtein AntigensT CellsInsulin ManagementDiabetes +13

The lymphopenia (lyp ) gene controls the intrathymic cytokine ratio in congenic BioBreeding rats

Sabine Bieg, Christer Möller, Tomas Olsson, +1

Diabetologia

ImmunogeneticsCongenic Biobreeding RatsAutoimmune DiseaseLymphocyte DevelopmentImmune Cell Development +6

Gad₆₅is recognized by t-cells, but not by antibodies from nod-mice

Sabine Bieg, L. Herberg, W Northemann, +1

Autoimmunity