Guihui Tu

Enhanced Chemotherapeutic Efficacy of PLGA-Encapsulated Epigallocatechin Gallate (EGCG) Against Human Lung Cancer

Lingyu Zhang, Wenshu Chen, Guihui Tu et al. · International Journal of Nanomedicine · 2020 · 80 citations · Full text

A PARP1 PROTAC as a novel strategy against PARP inhibitor resistance via promotion of ferroptosis in p53-positive breast cancer

Ge Li, Shanshan Lin, Zelei Yu et al. · Biochemical Pharmacology · 2022 · 54 citations

Breast Oncology, Medicine, Parp1 Protac +9

Discovery of BP3 as an efficacious proteolysis targeting chimera (PROTAC) degrader of HSP90 for treating breast cancer

Quanyu Liu, Guihui Tu, Yan Hu et al. · European Journal of Medicinal Chemistry · 2021 · 32 citations · Full text

Efficacious Proteolysis, Biochemistry, Natural Sciences +8

Discovery of CN0 as a novel proteolysis-targeting chimera (PROTAC) degrader of PARP1 that can activate the cGAS/STING immunity pathway combined with daunorubicin

Shanshan Lin, Guihui Tu, Zelei Yu et al. · Bioorganic & Medicinal Chemistry · 2022 · 20 citations

Protein Function, Cgas/sting Immunity Pathway, Biochemistry +6

Albumin-encapsulated HSP90-PROTAC BP3 nanoparticles not only retain protein degradation ability but also enhance the antitumour activity of BP3 <i>in vivo</i>

Qingna Jiang, Yan Hu, Quanyu Liu et al. · Journal of drug targeting · 2023 · 10 citations