Light-dependent regulation of structural flexibility in a photochromic fluorescent protein

Hideaki Mizuno, Tapas K. Mal, Markus Wälchli, +8

Proceedings of the National Academy of Sciences

LECT2 Functions as a Hepatokine That Links Obesity to Skeletal Muscle Insulin Resistance

Fei Lan, Hirofumi Misu, Keita Chikamoto, +23

Diabetes

Deficiency of the hepatokine selenoprotein P increases responsiveness to exercise in mice through upregulation of reactive oxygen species and AMP-activated protein kinase in muscle

Hirofumi Misu, Hiroaki Takayama, Yoshiro Saito, +22

Nature Medicine

InflammationHepatokine Selenoprotein PMolecular PhysiologyMuscle FunctionExercise +9

Proteasome Dysfunction Mediates Obesity-Induced Endoplasmic Reticulum Stress and Insulin Resistance in the Liver

Toshiki Otoda, Toshinari Takamura, Hirofumi Misu, +21

Diabetes

Phenoxyl radical complexes of chromium(III), manganese(III), cobalt(III), and nickel(II)

Jochen Müller, Akihiro Kikuchi, Eckhard Bill, +4

Inorganica Chimica Acta

Inorganic ChemistryCoordination ComplexMolecular ComplexChemistryPhenoxyl Radical Complexes +1

Transient Intermediates from Mn(salen) with Sterically Hindered Mesityl Groups: Interconversion between Mn^IV-Phenolate and Mn^III-Phenoxyl Radicals as an Origin for Unique Reactivity

Takuya Kurahashi, Akihiro Kikuchi, Takehiko Tosha, +3

Inorganic Chemistry

Metformin Suppresses Expression of the Selenoprotein P Gene via an AMP-activated Kinase (AMPK)/FoxO3a Pathway in H4IIEC3 Hepatocytes

Hiroaki Takayama, Hirofumi Misu, Hisakazu Iwama, +13

Journal of Biological Chemistry

Signal TransductionBiochemistryMedicineLiver PhysiologyNatural Sciences +11

Intestinal Absorption Mechanism of Tebipenem Pivoxil, a Novel Oral Carbapenem: Involvement of Human OATP Family in Apical Membrane Transport

Kazuhiko Kato, Yoshiyuki Shirasaka, Erika Kuraoka, +6

Molecular Pharmaceutics

Crystal structure of rat biliverdin reductase.

Akihiro Kikuchi, Sam‐Yong Park, Hideyuki Miyatake, +4

Nature Structural Biology

Crystal StructureBiochemistryProtein X-ray CrystallographyMedicineRedox Biology +1

Unique Properties and Reactivity of High-Valent Manganese−Oxo versus Manganese−Hydroxo in the Salen Platform

Takuya Kurahashi, Akihiro Kikuchi, Yoshitsugu Shiro, +2

Inorganic Chemistry