Aβ34 is a BACE1-derived degradation intermediate associated with amyloid clearance and Alzheimer’s disease progression

Filip Liebsch, Luka Kulic, Charlotte E. Teunissen, +14

Nature Communications

The amyloid-β degradation intermediate Aβ34 is pericyte-associated and reduced in brain capillaries of patients with Alzheimer’s disease

Tunahan Kirabali, Serena Rigotti, Alessandro Siccoli, +6

Acta Neuropathologica Communications

Neurodegenerative Disease-Related Proteins within the Epidermal Layer of the Human Skin

Sigvard Åkerman, Shireen Hossain, Adeola Shobo, +6

Journal of Alzheimer s Disease

Neurodegenerative Disease-related ProteinsNeurochemical BiomarkersCytoskeletonPeptide ScienceDermatology +20

Enhanced Brain Penetration of Pretomanid By Intranasal Administration of An Oil-in-Water Nanoemulsion

Adeola Shobo, Annapurna Pamreddy, Hendrik G. Kruger, +4

Nanomedicine

Tissue distribution of pretomanid in rat brain via mass spectrometry imaging

Adeola Shobo, Dominika Bratkowska, Sooraj Baijnath, +6

Xenobiotica

EngineeringPet-mriBiological Mass SpectrometryExperimental PharmacologyRat Brain +26

Evidence for the presence of clofazimine and its distribution in the healthy mouse brain

Sooraj Baijnath, Adeola Shobo, Chivonne Moodley, +7

Journal of Molecular Histology

NeuropsychologyPsychoactive DrugHealthy Mouse BrainPsychiatryNeurophysiology +12

Visualization of Time-Dependent Distribution of Rifampicin in Rat Brain Using MALDI MSI and Quantitative LCMS/MS

Adeola Shobo, Dominika Bratkowska, Sooraj Baijnath, +5

Assay and Drug Development Technologies

Determination of the antitubercular drug PA-824 in rat plasma, lung and brain tissues by liquid chromatography tandem mass spectrometry: Application to a pharmacokinetic study

Dominika Bratkowska, Adeola Shobo, Sanil D. Singh, +4

Journal of Chromatography B

Therapeutic Drug MonitoringAntitubercular Drug Pa-824BiochemistryMedicineBioanalysis +7

MALDI MSI and LC‐MS/MS: Towards preclinical determination of the neurotoxic potential of fluoroquinolones

Adeola Shobo, Sooraj Baijnath, Dominika Bratkowska, +6

Drug Testing and Analysis

NeurotoxicologyTowards Preclinical DeterminationNeurochemical BiomarkersAntimicrobial ChemotherapyPharmacodynamic Modeling +21

The downfall of TBA-354 – a possible explanation for its neurotoxicity <i>via</i> mass spectrometric imaging

Sphamandla Ntshangase, Adeola Shobo, Hendrik G. Kruger, +5

Xenobiotica