Spinal neuronal NOS activation mediates sigma‐1 receptor‐induced mechanical and thermal hypersensitivity in mice: involvement of PKC‐dependent GluN1 phosphorylation

Dae‐Hyun Roh, Sheu‐Ran Choi, Seo‐Yeon Yoon, +6

British Journal of Pharmacology

Pain MedicineSynaptic TransmissionNeuropathic PainMolecular PainNeurotransmission +25

σ1 receptors activate astrocytes via p38 <scp>MAPK</scp> phosphorylation leading to the development of mechanical allodynia in a mouse model of neuropathic pain

Ji Young Moon, Dae‐Hyun Roh, Seo Yeon Yoon, +8

British Journal of Pharmacology

Spinal sigma-1 receptors activate NADPH oxidase 2 leading to the induction of pain hypersensitivity in mice and mechanical allodynia in neuropathic rats

Sheu‐Ran Choi, Dae‐Hyun Roh, Seo Yeon Yoon, +8

Pharmacological Research

Mechanical AllodyniaPain SyndromeSpinal Cord InjuryHealth SciencesPain Medicine +12

Microglial interleukin-1β in the ipsilateral dorsal horn inhibits the development of mirror-image contralateral mechanical allodynia through astrocyte activation in a rat model of inflammatory pain

Hoon-Seong Choi, Dae‐Hyun Roh, Seo Yeon Yoon, +9

Pain

Pain DisordersPain MedicineMicroglial Interleukin-1βImmunologyNeuropathic Pain +26

Blockade of peripheral P2Y1 receptors prevents the induction of thermal hyperalgesia via modulation of TRPV1 expression in carrageenan-induced inflammatory pain rats: Involvement of p38 MAPK phosphorylation in DRGs

Soon Gu Kwon, Dae‐Hyun Roh, Seo Yeon Yoon, +7

Neuropharmacology

InflammationAnti-inflammatoryHealth SciencesPain MedicineMedicine +12

Astrocyte sigma-1 receptors modulate connexin 43 expression leading to the induction of below-level mechanical allodynia in spinal cord injured mice

Sheu‐Ran Choi, Dae‐Hyun Roh, Seo Yeon Yoon, +5

Neuropharmacology

Spinal Cord InjuryAstrocyte Sigma-1 ReceptorsConnexin 43NeuroscienceMolecular Neurobiology +5

Spinal D-Serine Increases PKC-Dependent GluN1 Phosphorylation Contributing to the Sigma-1 Receptor-Induced Development of Mechanical Allodynia in a Mouse Model of Neuropathic Pain

Sheu‐Ran Choi, Ji-Young Moon, Dae‐Hyun Roh, +7

Journal of Pain

Mechanical AllodyniaHealth SciencesMedicinePhysiologyNeuropathic Pain +7

The role of spinal interleukin-1β and astrocyte connexin 43 in the development of mirror-image pain in an inflammatory pain model

Hoon-Seong Choi, Dae‐Hyun Roh, Seo Yeon Yoon, +8

Experimental Neurology

InflammationPain SyndromePain DisordersAstrocyte Connexin 43Health Sciences +11

Acid Evoked Thermal Hyperalgesia Involves Peripheral P2Y1 Receptor Mediated TRPV1 Phosphorylation in a Rodent Model of Thrombus Induced Ischemic Pain

Soon Gu Kwon, Dae‐Hyun Roh, Seo Yeon Yoon, +8

Molecular Pain

Sigma-1 receptor-mediated increase in spinal p38 MAPK phosphorylation leads to the induction of mechanical allodynia in mice and neuropathic rats

Ji-Young Moon, Dae‐Hyun Roh, Seo Yeon Yoon, +7

Experimental Neurology

Mechanical AllodyniaSpinal Cord InjuryMolecular PhysiologyHealth SciencesPhysiology +10