Minoru Ishikawa

Protein Knockdown Using Methyl Bestatin−Ligand Hybrid Molecules: Design and Synthesis of Inducers of Ubiquitination-Mediated Degradation of Cellular Retinoic Acid-Binding Proteins

Yukihiro Itoh, Minoru Ishikawa, Mikihiko Naito et al. · Journal of the American Chemical Society · 2010 · 378 citations

Molecular Regulation, Apoptosis, Ubiquitination-mediated Degradation +18

Discovery of Small Molecules that Induce the Degradation of Huntingtin

Shusuke Tomoshige, S. Nomura, Kenji Ohgane et al. · Angewandte Chemie International Edition · 2017 · 140 citations

Design, synthesis and biological evaluation of nuclear receptor-degradation inducers

Yukihiro Itoh, Risa Kitaguchi, Minoru Ishikawa et al. · Bioorganic & Medicinal Chemistry · 2011 · 137 citations

Signal Transduction, Natural Sciences, Receptor (Biochemistry) +3

Specific degradation of CRABP-II via cIAP1-mediated ubiquitylation induced by hybrid molecules that crosslink cIAP1 and the target protein

Keiichiro Okuhira, Nobumichi Ohoka, Kimie Sai et al. · FEBS Letters · 2011 · 114 citations

Proximity Histidine Labeling by Umpolung Strategy Using Singlet Oxygen

Keita Nakane, Shinichi Sato, Tatsuya Niwa et al. · Journal of the American Chemical Society · 2021 · 109 citations