Julia Jabs

Screening drug effects in patient‐derived cancer cells links organoid responses to genome alterations

Julia Jabs, Franziska Maria Zickgraf, Jeongbin Park et al. · Molecular Systems Biology · 2017 · 198 citations · Full text

Medicine, Bioinformatics, Oncology +15

Patient-specific modeling of stroma-mediated chemoresistance of pancreatic cancer using a three-dimensional organoid-fibroblast co-culture system

Sebastian Schuth, Solange Le Blanc, Teresa G. Krieger et al. · Journal of Experimental & Clinical Cancer Research · 2022 · 146 citations · Full text

Medicine, Cancer Biology, Oncology +17

Single-cell analysis of patient-derived PDAC organoids reveals cell state heterogeneity and a conserved developmental hierarchy

Teresa G. Krieger, Solange Le Blanc, Julia Jabs et al. · Nature Communications · 2021 · 119 citations · Full text

Medicine, Cancer Biology, Oncology +17

Single-cell analysis of patient-derived PDAC organoids reveals cell state heterogeneity and a conserved developmental hierarchy

Teresa G. Krieger, Solange Le Blanc, Julia Jabs et al. · bioRxiv (Cold Spring Harbor Laboratory) · 2020 · 16 citations · Full text

Medicine, Cancer Biology, Oncology +17

A spheroid whole mount drug testing pipeline with machine-learning based image analysis identifies cell-type specific differences in drug efficacy on a single-cell level

Mario Vitacolonna, Roman Bruch, Richard Schneider et al. · BMC Cancer · 2024 · 10 citations · Full text

Medicine, Cell Biology, Oncology +16