Patient-specific modeling of stroma-mediated chemoresistance of pancreatic cancer using a three-dimensional organoid-fibroblast co-culture system

Sebastian Schuth, Solange Le Blanc, Teresa G. Krieger, +7

Journal of Experimental & Clinical Cancer Research

Heme carrier protein 1 transports heme and is involved in heme-Fe metabolism

Solange Le Blanc, Michael D. Garrick, Miguel Arredondo

American Journal of Physiology-Cell Physiology

Single-cell analysis of patient-derived PDAC organoids reveals cell state heterogeneity and a conserved developmental hierarchy

Teresa G. Krieger, Solange Le Blanc, Julia Jabs, +9

Nature Communications

Iron, Copper, and Zinc Transport: Inhibition of Divalent Metal Transporter 1 (DMT1) and Human Copper Transporter 1 (hCTR1) by shRNA

Alejandra Araya Espinoza, Solange Le Blanc, Manuel Olivares, +3

Biological Trace Element Research

Zinc TransportMolecular PhysiologyBiochemistryIron MetabolismNatural Sciences +7

Heparin affects human bone marrow stromal cell fate: Promoting osteogenic and reducing adipogenic differentiation and conversion

Meike Simann, Verena Schneider, Solange Le Blanc, +6

Bone

SclerostinDevelopmental BiologyAdipogenic DifferentiationBone Morphogenic ProteinMedicine +5

Canonical FGFs Prevent Osteogenic Lineage Commitment and Differentiation of Human Bone Marrow Stromal Cells Via ERK1/2 Signaling

Meike Simann, Solange Le Blanc, Verena Schneider, +5

Journal of Cellular Biochemistry

SclerostinEngineeringOsteogenesisFgf AdditionOsteoporosis +17

Fibroblast growth factors 1 and 2 inhibit adipogenesis of human bone marrow stromal cells in 3D collagen gels

Solange Le Blanc, Meike Simann, Franz Jakob, +2

Experimental Cell Research

Tissue EngineeringRegenerative MedicineFibrosisDevelopmental BiologyInhibit Adipogenesis +7

Type 2 diabetic patients and their offspring show altered parameters of iron status, oxidative stress and genes related to mitochondrial activity

Solange Le Blanc, Pía Villarroel, Valeria Candia, +4

BioMetals

Metabolic SyndromeMetabolic DisorderMitochondrial FunctionMitochondrial ActivityGenetics +8

Single-cell analysis of patient-derived PDAC organoids reveals cell state heterogeneity and a conserved developmental hierarchy

Teresa G. Krieger, Solange Le Blanc, Julia Jabs, +9

Heme Iron Uptake by Caco-2 Cells is a Saturable, Temperature Sensitive and Modulated by Extracellular pH and Potassium

Miguel Arredondo, Janneke Kloosterman, Sergio Núñez, +6

Biological Trace Element Research

Temperature SensitiveCaco-2 CellsBiochemistryHeme HomeostasisIron Metabolism +10