Samantha J. Clarke

Sanglifehrin A Acts as a Potent Inhibitor of the Mitochondrial Permeability Transition and Reperfusion Injury of the Heart by Binding to Cyclophilin-D at a Different Site from Cyclosporin A

Samantha J. Clarke, Gavin P. McStay, Andrew P. Halestrap · Journal of Biological Chemistry · 2002 · 369 citations · Full text

Life Sciences, Biochemistry, Pharmacology +16

Role of critical thiol groups on the matrix surface of the adenine nucleotide translocase in the mechanism of the mitochondrial permeability transition pore

Gavin P. McStay, Samantha J. Clarke, Andrew P. Halestrap · Biochemical Journal · 2002 · 356 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +17

Ischaemic Preconditioning Inhibits Opening of Mitochondrial Permeability Transition Pores in the Reperfused Rat Heart

Sabzali Javadov, Samantha J. Clarke, Manika Das et al. · The Journal of Physiology · 2003 · 345 citations · Full text

Life Sciences, Cardiology, Physiology +17

The effects of ischaemic preconditioning, diazoxide and 5‐hydroxydecanoate on rat heart mitochondrial volume and respiration

Kelvin Lim, Sabzali Javadov, Manika Das et al. · The Journal of Physiology · 2002 · 220 citations · Full text

Life Sciences, Biochemistry, Physiology +17

Inhibition of Mitochondrial Permeability Transition Pore Opening by Ischemic Preconditioning Is Probably Mediated by Reduction of Oxidative Stress Rather Than Mitochondrial Protein Phosphorylation

Samantha J. Clarke, Igor Khaliulin, Manika Das et al. · Circulation Research · 2008 · 157 citations · Full text

Life Sciences, Biochemistry, Cell Biology +17