Structure of the human voltage-gated sodium channel Na _v 1.4 in complex with β1

Xiaojing Pan, Zhangqiang Li, Qiang Zhou, +11

Science

Synaptic TransmissionNeurotransmitterMolecular BiologyCell PolarizationNeurotransmission +21

Structural basis for high-voltage activation and subtype-specific inhibition of human Na_v1.8

Xiaoshuang Huang, Xueqin Jin, Gaoxingyu Huang, +7

Proceedings of the National Academy of Sciences

High-resolution structures of human Nav1.7 reveal gating modulation through α-π helical transition of S6IV

Gaoxingyu Huang, Dongliang Liu, Weipeng Wang, +5

Cell Reports

Structural basis for human Cav1.2 inhibition by multiple drugs and the neurotoxin calciseptine

Shuai Gao, Xia Yao, Jiaofeng Chen, +15

Cell

Molecular PharmacologyMolecular PhysiologyBiochemistryMedicinePhysiology +10

Template-independent genome editing in the Pcdh15 mouse, a model of human DFNB23 nonsyndromic deafness

Lian Liu, Linzhi Zou, Kuan Li, +16

Cell Reports

TMC1 is an essential component of a leak channel that modulates tonotopy and excitability of auditory hair cells in mice

Shuang Liu, Shufeng Wang, Linzhi Zou, +7

eLife

MechanotransductionNeurotransmissionMouse Hair CellsCellular PhysiologySocial Sciences +20

PIEZO2 mediates ultrasonic hearing via cochlear outer hair cells in mice

Jie Li, Shuang Liu, Chenmeng Song, +17

Proceedings of the National Academy of Sciences

Structural basis for human Cav3.2 inhibition by selective antagonists

Jian Huang, Xiao Fan, Xueqin Jin, +7

Cell Research

Structural basis for the severe adverse interaction of sofosbuvir and amiodarone on L-type Cav channels

Xia Yao, Shuai Gao, Jixin Wang, +12

Cell

Molecular PharmacologyMedicineIon ChannelsStructural BasisL-type Cav Channels +3

Identification of a Novel ENU-Induced Mutation in Mouse<i>Tbx1</i>Linked to Human DiGeorge Syndrome

Jiaofeng Chen, Xue Zhang, Jie Li, +3

Neural Plasticity