Neil Mathias

pH-Dependent Dissolution in Vitro and Absorption in Vivo of Weakly Basic Drugs: Development of a Canine Model

Rong Zhou, Paul Moench, Christopher L. Heran et al. · Pharmaceutical Research · 2005 · 117 citations

Pharmaceutical Science, Pharmacological Study, Medicine +9

Solution Behavior of PVP-VA and HPMC-AS-Based Amorphous Solid Dispersions and Their Bioavailability Implications

Feng Qian, Jennifer Wang, Ruiling Hartley et al. · Pharmaceutical Research · 2012 · 101 citations

Materials Science, Chemical Engineering, Engineering +7

Respiratory epithelial cell culture models for evaluation of ion and drug transport

Neil Mathias, Fumiyoshi Yamashita, Vincent H.L. Lee · Advanced Drug Delivery Reviews · 1996 · 65 citations

Lung Deposition, Respiratory Toxicology, Medicine +7

Assessing the Risk of pH-Dependent Absorption for New Molecular Entities: A Novel <i>in Vitro</i> Dissolution Test, Physicochemical Analysis, and Risk Assessment Strategy

Neil Mathias, Yan Xu, Dhaval Patel et al. · Molecular Pharmaceutics · 2013 · 64 citations

Pharmaceutical Science, Chemical Contaminant, Risk Assessment Strategy +19

Discovery of (R)-N-(3-(7-methyl-1H-indazol-5-yl)-1-(4-(1-methylpiperidin-4-yl)-1-oxopropan-2-yl)-4-(2-oxo-1,2-dihydroquinolin-3-yl)piperidine-1-carboxamide (BMS-742413): A potent human CGRP antagonist with superior safety profile for the treatment of migraine through intranasal delivery

Prasad V. Chaturvedula, Stephen E. Mercer, Sokhom S. Pin et al. · Bioorganic & Medicinal Chemistry Letters · 2013 · 60 citations · Full text

Superior Safety Profile, Medicinal Chemistry, Medicine +6