Janet R. Manning

Adropin regulates pyruvate dehydrogenase in cardiac cells via a novel GPCR-MAPK-PDK4 signaling pathway

Dharendra Thapa, Michael W. Stoner, Manling Zhang et al. · Redox Biology · 2018 · 92 citations · Full text

The protein acetylase GCN5L1 modulates hepatic fatty acid oxidation activity via acetylation of the mitochondrial β-oxidation enzyme HADHA

Dharendra Thapa, Kaiyuan Wu, Michael W. Stoner et al. · Journal of Biological Chemistry · 2018 · 92 citations · Full text

Protein Acetylase Gcn5l1, Mitochondrial Function, Biochemistry +8

Acetylation of mitochondrial proteins by GCN5L1 promotes enhanced fatty acid oxidation in the heart

Dharendra Thapa, Manling Zhang, Janet R. Manning et al. · American Journal of Physiology-Heart and Circulatory Physiology · 2017 · 86 citations · Full text

Adropin treatment restores cardiac glucose oxidation in pre-diabetic obese mice

Dharendra Thapa, Bingxian Xie, Manling Zhang et al. · Journal of Molecular and Cellular Cardiology · 2019 · 74 citations · Full text

Obesity, Metabolic Syndrome, Diabetes Management +12

Loss of GCN5L1 in cardiac cells disrupts glucose metabolism and promotes cell death via reduced Akt/mTORC2 signaling

Janet R. Manning, Dharendra Thapa, Manling Zhang et al. · Biochemical Journal · 2019 · 64 citations · Full text