Recombinant NY-ESO-1 protein with ISCOMATRIX adjuvant induces broad integrated antibody and CD4+ and CD8+ T cell responses in humans

Ian D. Davis, Weisan Chen, Heather Jackson, +25

Proceedings of the National Academy of Sciences

MEK Inhibition, Alone or in Combination with BRAF Inhibition, Affects Multiple Functions of Isolated Normal Human Lymphocytes and Dendritic Cells

Laura J. Vella, Anupama Pasam, Nektaria Dimopoulos, +7

Cancer Immunology Research

Immune RegulationImmunologyImmunologic MechanismInnate ImmunityImmunotherapy +18

The impact of imiquimod, a Toll-like receptor-7 ligand (TLR7L), on the immunogenicity of melanoma peptide vaccination with adjuvant Flt3 ligand.

Mark Shackleton, Ian D. Davis, Wendie Hopkins, +11

PubMed

ImmunologyImmunoeditingAdjuvant Flt3 LigandImmunotherapeuticsCd4 T Cell Responses +16

Regulatory T-Cell–Mediated Attenuation of T-Cell Responses to the NY-ESO-1 ISCOMATRIX Vaccine in Patients with Advanced Malignant Melanoma

Theo Nicholaou, Lisa M. Ebert, Ian D. Davis, +12

Clinical Cancer Research

Melan-A–specific Cytotoxic T Cells Are Associated with Tumor Regression and Autoimmunity Following Treatment with Anti-CTLA-4

Oliver Klein, Lisa M. Ebert, Theo Nicholaou, +11

Clinical Cancer Research

Immunodominant CD4 ⁺ responses identified in a patient vaccinated with full-length NY-ESO-1 formulated with ISCOMATRIX adjuvant

Qiyuan Chen, Heather Jackson, Phillip Parente, +17

Proceedings of the National Academy of Sciences

Cross‐priming of CD8⁺ T cells by viral and tumor antigens is a robust phenomenon

Weisan Chen, Kelly‐Anne Masterman, Sameh Basta, +5

European Journal of Immunology

Adaptive Immune SystemImmunologyImmune RegulationImmunodominanceImmunologic Mechanism +24

Reversal in the Immunodominance Hierarchy in Secondary CD8+ T Cell Responses to Influenza A Virus: Roles for Cross-Presentation and Lysis-Independent Immunodomination

Weisan Chen, Ken C. Pang, Kelly‐Anne Masterman, +7

The Journal of Immunology

Blood Dendritic Cells Generated With Flt3 Ligand and CD40 Ligand Prime CD8+ T Cells Efficiently in Cancer Patients

Ian D. Davis, Qiyuan Chen, Leone Morris, +17

Journal of Immunotherapy

T-regulatory CellImmunologyCd4 T Cell ResponsesCancer PatientsImmunotherapy +15

Structural Determinants of Aldosterone Binding Selectivity in the Mineralocorticoid Receptor

Fraser M. Rogerson, Nektaria Dimopoulos, Pavel Sluka, +3

Journal of Biological Chemistry