Anthony Cruz

Hidden bias in the DUD-E dataset leads to misleading performance of deep learning in structure-based virtual screening

Lieyang Chen, Anthony Cruz, Steven Ramsey et al. · PLoS ONE · 2019 · 268 citations · Full text

Pharmacy, Bioinformatics, Molecular Biology +17

Src activation by β-adrenoreceptors is a key switch for tumour metastasis

Guillermo N. Armaiz-Peña, Julie K. Allen, Anthony Cruz et al. · Nature Communications · 2013 · 202 citations · Full text

Medicine, Cancer Biology, Oncology +10

Thermodynamics of Water in an Enzyme Active Site: Grid-Based Hydration Analysis of Coagulation Factor Xa

Crystal N. Nguyen, Anthony Cruz, Michael K. Gilson et al. · Journal of Chemical Theory and Computation · 2014 · 140 citations · Full text

Life Sciences, Biochemistry, Biophysics +17

Testing inhomogeneous solvation theory in structure-based ligand discovery

Trent E. Balius, Marcus Fischer, Reed M. Stein et al. · Proceedings of the National Academy of Sciences · 2017 · 88 citations · Full text

Natural Sciences, Chemistry, Medicinal Chemistry +17

Model for the Peptide-Free Conformation of Class II MHC Proteins

Corrie Painter, Anthony Cruz, Gustavo E. López et al. · PLoS ONE · 2008 · 65 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +17